P59259 · H4_ARATH

Function

function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Features

Showing features for dna binding.

1103102030405060708090100
TypeIDPosition(s)Description
DNA binding17-21

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast
Cellular Componentcytosol
Cellular Componentextracellular region
Cellular Componentnucleolus
Cellular Componentnucleosome
Cellular Componentperoxisome
Cellular Componentplant-type vacuole
Cellular Componentplasma membrane
Cellular Componentplasmodesma
Cellular Componentplastid
Cellular Componentthylakoid
Molecular FunctionDNA binding
Molecular Functionprotein heterodimerization activity
Molecular Functionstructural constituent of chromatin
Biological Processresponse to water deprivation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Histone H4

Gene names

    • ORF names
      F24B9.25
    • Ordered locus names
      At1g07660
    • ORF names
      F24B9.8
    • Ordered locus names
      At1g07820
    • ORF names
      F8N16.2, T11P11.4
    • Ordered locus names
      At2g28740
    • ORF names
      F16L2_140
    • Ordered locus names
      At3g45930
    • ORF names
      F18L15.40
    • Ordered locus names
      At3g46320

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    P59259
  • Secondary accessions
    • P02308

Proteomes

    • Identifier
    • Component
      Chromosome 1, Chromosome 2, Chromosome 3, Chromosome 5

Organism-specific databases

Genome annotation databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001582781-103Histone H4

Post-translational modification

May be acetylated by MBD9.

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with ORTH2 (PubMed:17242155).
Interacts with AHL27 (PubMed:24218605).

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-20Disordered

Sequence similarities

Belongs to the histone H4 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

P59259-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    103
  • Mass (Da)
    11,409
  • Last updated
    2007-01-23 v2
  • Checksum
    A9FD57725A2A7598
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A8MRV1A8MRV1_ARATHAt1g0766086

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M17132
EMBL· GenBank· DDBJ
AAA32810.1
EMBL· GenBank· DDBJ
Genomic DNA
M17133
EMBL· GenBank· DDBJ
AAA32811.1
EMBL· GenBank· DDBJ
Genomic DNA
AC007583
EMBL· GenBank· DDBJ
AAF75089.1
EMBL· GenBank· DDBJ
Genomic DNA
AC007583
EMBL· GenBank· DDBJ
AAF75072.1
EMBL· GenBank· DDBJ
Genomic DNA
AC005727
EMBL· GenBank· DDBJ
AAC79580.1
EMBL· GenBank· DDBJ
Genomic DNA
AC007184
EMBL· GenBank· DDBJ
AAM15445.1
EMBL· GenBank· DDBJ
Genomic DNA
AL162459
EMBL· GenBank· DDBJ
CAB82817.1
EMBL· GenBank· DDBJ
Genomic DNA
AL133298
EMBL· GenBank· DDBJ
CAB62023.1
EMBL· GenBank· DDBJ
Genomic DNA
AL132960
EMBL· GenBank· DDBJ
CAB88335.1
EMBL· GenBank· DDBJ
Genomic DNA
AB006705
EMBL· GenBank· DDBJ
BAB09507.1
EMBL· GenBank· DDBJ
Genomic DNA
AB015475
EMBL· GenBank· DDBJ
BAB08365.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE28158.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE28187.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE28188.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC08165.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE78091.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE78146.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE79133.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED97220.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED97260.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
ANM70482.1
EMBL· GenBank· DDBJ
Genomic DNA
AF325058
EMBL· GenBank· DDBJ
AAG40410.1
EMBL· GenBank· DDBJ
mRNA
AF334729
EMBL· GenBank· DDBJ
AAG50107.1
EMBL· GenBank· DDBJ
mRNA
AY057609
EMBL· GenBank· DDBJ
AAL14404.1
EMBL· GenBank· DDBJ
mRNA
AY062717
EMBL· GenBank· DDBJ
AAL32795.1
EMBL· GenBank· DDBJ
mRNA
AY063857
EMBL· GenBank· DDBJ
AAL36213.1
EMBL· GenBank· DDBJ
mRNA
AY093353
EMBL· GenBank· DDBJ
AAM13352.1
EMBL· GenBank· DDBJ
mRNA
AY099675
EMBL· GenBank· DDBJ
AAM20526.1
EMBL· GenBank· DDBJ
mRNA
AY124836
EMBL· GenBank· DDBJ
AAM70545.1
EMBL· GenBank· DDBJ
mRNA
AY128855
EMBL· GenBank· DDBJ
AAM91255.1
EMBL· GenBank· DDBJ
mRNA
AY142651
EMBL· GenBank· DDBJ
AAN13189.1
EMBL· GenBank· DDBJ
mRNA
AY085175
EMBL· GenBank· DDBJ
AAM61726.1
EMBL· GenBank· DDBJ
mRNA
AY085495
EMBL· GenBank· DDBJ
AAM62721.1
EMBL· GenBank· DDBJ
mRNA
AY085965
EMBL· GenBank· DDBJ
AAM63175.1
EMBL· GenBank· DDBJ
mRNA
AY086789
EMBL· GenBank· DDBJ
AAM63839.1
EMBL· GenBank· DDBJ
mRNA
AY086185
EMBL· GenBank· DDBJ
AAM64264.1
EMBL· GenBank· DDBJ
mRNA
AY087061
EMBL· GenBank· DDBJ
AAM64622.1
EMBL· GenBank· DDBJ
mRNA
AY087188
EMBL· GenBank· DDBJ
AAM64744.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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