P59004 · PYRH_CORGL
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids243 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 18-21 | ATP (UniProtKB | ChEBI) | |||
Binding site | 59 | UMP (UniProtKB | ChEBI) | |||
Binding site | 60 | ATP (UniProtKB | ChEBI) | |||
Binding site | 64 | ATP (UniProtKB | ChEBI) | |||
Binding site | 79 | UMP (UniProtKB | ChEBI) | |||
Binding site | 140-147 | UMP (UniProtKB | ChEBI) | |||
Binding site | 173 | ATP (UniProtKB | ChEBI) | |||
Binding site | 176 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionP59004
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000143840 | 1-243 | Uridylate kinase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length243
- Mass (Da)26,183
- Last updated2002-08-30 v1
- ChecksumD30990FB4796D294
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000036 EMBL· GenBank· DDBJ | BAB99417.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BX927154 EMBL· GenBank· DDBJ | CAF20364.1 EMBL· GenBank· DDBJ | Genomic DNA |