P59004 · PYRH_CORGL

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site18-21ATP (UniProtKB | ChEBI)
Binding site59UMP (UniProtKB | ChEBI)
Binding site60ATP (UniProtKB | ChEBI)
Binding site64ATP (UniProtKB | ChEBI)
Binding site79UMP (UniProtKB | ChEBI)
Binding site140-147UMP (UniProtKB | ChEBI)
Binding site173ATP (UniProtKB | ChEBI)
Binding site176ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • Ordered locus names
      Cgl2024, cg2218

Organism names

Accessions

  • Primary accession
    P59004

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001438401-243Uridylate kinase

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    243
  • Mass (Da)
    26,183
  • Last updated
    2002-08-30 v1
  • Checksum
    D30990FB4796D294
MTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKTGAEIAVVIGGGNFFRGAELQQRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGCDVLLMAKAVDGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIARAISGERIGTLVES

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000036
EMBL· GenBank· DDBJ
BAB99417.1
EMBL· GenBank· DDBJ
Genomic DNA
BX927154
EMBL· GenBank· DDBJ
CAF20364.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help