P58733 · IPYR_PSEAO

Function

function

Hydrolyzes PPi generated in anabolic reactions.
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
2.9 μMPPi

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site28substrate
Binding site42substrate
Binding site54substrate
Binding site66Mg2+ 1 (UniProtKB | ChEBI)
Binding site71Mg2+ 1 (UniProtKB | ChEBI)
Binding site71Mg2+ 2 (UniProtKB | ChEBI)
Binding site102Mg2+ 1 (UniProtKB | ChEBI)
Binding site139substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Biological Processphosphate-containing compound metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inorganic pyrophosphatase
  • EC number
  • Alternative names
    • Pyrophosphate phospho-hydrolase
      (PPase
      )

Gene names

    • Name
      ppa

Organism names

Accessions

  • Primary accession
    P58733
  • Secondary accessions
    • P80898

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001375191-180Inorganic pyrophosphatase

Interaction

Subunit

Homohexamer.

Structure

Family & Domains

Sequence similarities

Belongs to the PPase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    180
  • Mass (Da)
    20,332
  • Last updated
    2002-02-11 v1
  • Checksum
    F2A84DC1A9038A42
MDLSRIPPQPKAGILNVLIEIPAGSKNKYEFDKDLNAFALDRVLYSSVQYPYDYGFVPITNNLADDGDPLDGMVIMVPPTFPGVATARPIGMLQMVDGGDRDEKFLCVPAKDPRYTYVKSANDLAGHRLDEIFEFFRSYKNLFKKPTEFFGWKGDVAGLPLVEECVKNYYKTYCKNDHGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ252205
EMBL· GenBank· DDBJ
CAC81006.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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