P58109 · TF2B2_THEKO

Function

function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

Features

Showing features for binding site.

130620406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site10Zn2+ (UniProtKB | ChEBI)
Binding site13Zn2+ (UniProtKB | ChEBI)
Binding site29Zn2+ (UniProtKB | ChEBI)
Binding site32Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenttranscription preinitiation complex
Molecular FunctionDNA-binding transcription factor activity
Molecular FunctionTBP-class protein binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription initiation
Biological Processtranscription preinitiation complex assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription initiation factor IIB 2
  • Short names
    TFIIB 2

Gene names

    • Name
      tfb2
    • Synonyms
      tfb
    • Ordered locus names
      TK2287

Organism names

Accessions

  • Primary accession
    P58109

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001193301-306Transcription initiation factor IIB 2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for zinc finger, repeat.

TypeIDPosition(s)Description
Zinc finger6-37TFIIB-type
Repeat123-2061
Repeat217-2982

Sequence similarities

Belongs to the TFIIB family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    34,481
  • Last updated
    2001-06-01 v1
  • Checksum
    21B0DA89C5546F9D
MRGISPKRVCPICGSTEFIYDPRRGEIVCAKCGYVIEENVVDEGPEWRAFEPGQREKRARTGAPMTLMIHDKGLSTDIDWRDKDIHGNQITGMYRNKLRRLRMWQRRMRINDAAERNLAFALSELDRMAAQLRLPRHLKEVAASLYRKAVMKKLIRGRSIEGMVSAALYAACRMEGIPRTLDEIASVSKVSKKEIGRSYRFMARGLGLNLRPTSPIEYVDRFGDALGVSARTKKRAKEILNEAIKRGITSGKGPTGLAAAALYIAALLEGEKKTQREVAEVAHVTEVTVRNRYKELVEKLGINVPI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB046423
EMBL· GenBank· DDBJ
BAB21262.1
EMBL· GenBank· DDBJ
Genomic DNA
AP006878
EMBL· GenBank· DDBJ
BAD86476.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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