Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells.Wilson A.L., Sheridan K.M., Erdman R.A., Maltese W.A.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCBiochem. J. 318:1007-1014 (1996)Cited in1Mapped to63
Nucleotide dependence of Rab geranylgeranylation. Rab escort protein interacts preferentially with GDP-bound Rab.Seabra M.C.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCJ Biol Chem 271:14398-14404 (1996)Mapped to64
Mechanism of digeranylgeranylation of Rab proteins. Formation of a complex between monogeranylgeranyl-Rab and Rab escort protein.Shen F., Seabra M.C.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCJ Biol Chem 271:3692-3698 (1996)Mapped to64
cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein.Andres D.A., Seabra M.C., Brown M.S., Armstrong S.A., Smeland T.E., Cremers F.P.M., Goldstein J.L.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711PubMedEurope PMCCell 73:1091-1099 (1993)Cited in1Mapped to69
Isoprenylation of Rab proteins possessing a C-terminal CaaX motif.Joberty G., Tavitian A., Zahraoui A.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCFEBS Lett. 330:323-328 (1993)Cited in2Mapped to62
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins.Ullrich O., Stenmark H., Alexandrov K., Huber L.A., Kaibuchi K., Sasaki T., Takai Y., Zerial M.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCJ Biol Chem 268:18143-18150 (1993)Mapped to64
Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange.Soldati T., Shapiro A.D., Svejstrup A.B., Pfeffer S.R.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCNature 369:76-78 (1994)Mapped to64
Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A.Farnsworth C.C., Seabra M.C., Ericsson L.H., Gelb M.H., Glomset J.A.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 91:11963-11967 (1994)Cited in5Mapped to59
Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.Alexandrov K., Horiuchi H., Steele-Mortimer O., Seabra M.C., Zerial M.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCEMBO J. 13:5262-5273 (1994)Cited in1Mapped to63
Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases.Ishida M., E Oguchi M., Fukuda M.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873999, Reactome: R-HSA-8877740PubMedEurope PMCCell Struct Funct 41:61-79 (2016)Mapped to76
Rab proteins and the compartmentalization of the endosomal system.Wandinger-Ness A., Zerial M.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCCold Spring Harb Perspect Biol 6:a022616-a022616 (2014)Mapped to99+
Large-scale top down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.Catherman A.D., Durbin K.R., Ahlf D.R., Early B.P., Fellers R.T., Tran J.C., Thomas P.M., Kelleher N.L.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCMol. Cell. Proteomics 12:3465-3473 (2013)Cited in4Mapped to62
Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.Bultema J.J., Di Pietro S.M.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873999, Reactome: R-HSA-8877740PubMedEurope PMCSmall GTPases 4:16-21 (2013)Mapped to99
Rab GTPases as coordinators of vesicle traffic.Stenmark H.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCNat. Rev. Mol. Cell Biol. 10:513-525 (2009)Cited in2Mapped to99+
Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate.Baron R.A., Seabra M.C.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCBiochem. J. 415:67-75 (2008)Cited in3Mapped to62
Towards complete sets of farnesylated and geranylgeranylated proteins.Maurer-Stroh S., Koranda M., Benetka W., Schneider G., Sirota F.L., Eisenhaber F.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCPLoS Comput. Biol. 3:634-648 (2007)Cited in5Mapped to64
Isoprenoid modification of rab proteins terminating in CC or CXC motifs.Khosravi-Far R., Lutz R.J., Cox A.D., Conroy L., Bourne J.R., Sinensky M., Balch W.E., Buss J.E., Der C.J.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 88:6264-6268 (1991)Cited in5Mapped to62
Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1.Thoma N.H., Iakovenko A., Goody R.S., Alexandrov K.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711PubMedEurope PMCJ. Biol. Chem. 276:48637-48643 (2001)Cited in3Mapped to64
Membrane targeting of a Rab GTPase that fails to associate with Rab escort protein (REP) or guanine nucleotide dissociation inhibitor (GDI).Overmeyer J.H., Wilson A.L., Maltese W.A.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711, Reactome: R-HSA-8873999PubMedEurope PMCJ. Biol. Chem. 276:20379-20386 (2001)Cited in2Mapped to63
Allosteric regulation of substrate binding and product release in geranylgeranyltransferase type II.Thoma N.H., Iakovenko A., Kalinin A., Waldmann H., Goody R.S., Alexandrov K.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-8873711PubMedEurope PMCBiochemistry 40:268-274 (2001)Mapped to64