P57699 · KDPB_HALSA
- ProteinPotassium-transporting ATPase ATP-binding subunit
- GenekdpB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids719 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
Catalytic activity
- K+(out) + ATP + H2O = K+(in) + ADP + phosphate + H+This reaction proceeds in the forward direction.K+ (out)CHEBI:29103
+ CHEBI:30616 + CHEBI:15377 = K+ (in)CHEBI:29103+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 318 | 4-aspartylphosphate intermediate | |||
Binding site | 355 | ATP (UniProtKB | ChEBI) | |||
Binding site | 359 | ATP (UniProtKB | ChEBI) | |||
Binding site | 416-423 | ATP (UniProtKB | ChEBI) | |||
Binding site | 435 | ATP (UniProtKB | ChEBI) | |||
Binding site | 554 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 558 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | P-type potassium transmembrane transporter activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePotassium-transporting ATPase ATP-binding subunit
- EC number
- Alternative names
Gene names
Encoded on
- Plasmid pNRC200
Organism names
- Strain
- Taxonomic lineageArchaea > Methanobacteriati > Methanobacteriota > Stenosarchaea group > Halobacteria > Halobacteriales > Halobacteriaceae > Halobacterium > Halobacterium salinarum NRC-34001
Accessions
- Primary accessionP57699
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 35-55 | Helical | |||
Transmembrane | 62-82 | Helical | |||
Transmembrane | 228-248 | Helical | |||
Transmembrane | 254-274 | Helical | |||
Transmembrane | 624-644 | Helical | |||
Transmembrane | 652-672 | Helical | |||
Transmembrane | 698-718 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000046151 | 1-719 | Potassium-transporting ATPase ATP-binding subunit | ||
Keywords
- PTM
Interaction
Subunit
The system is composed of three essential subunits: KdpA, KdpB and KdpC.
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 372-396 | Disordered | |||
Compositional bias | 373-383 | Polar residues | |||
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length719
- Mass (Da)75,986
- Last updated2000-12-08 v1
- MD5 Checksum554E8C93E8FA3C92E5441D76B1F4D8D9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 373-383 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE004438 EMBL· GenBank· DDBJ | AAG20844.1 EMBL· GenBank· DDBJ | Genomic DNA |