P57396 · AROA_BUCAI
- Protein3-phosphoshikimate 1-carboxyvinyltransferase
- GenearoA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids427 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Catalytic activity
- 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphateThis reaction proceeds in the forward direction.
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 23 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 23 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 24 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 28 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 97 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 125 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 170 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 171 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 172 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 172 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 198 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Active site | 314 | Proton acceptor | |||
Binding site | 314 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 337 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 341 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 345 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 387 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 412 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 3-phosphoshikimate 1-carboxyvinyltransferase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-phosphoshikimate 1-carboxyvinyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Erwiniaceae > Buchnera
Accessions
- Primary accessionP57396
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000088235 | 1-427 | 3-phosphoshikimate 1-carboxyvinyltransferase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length427
- Mass (Da)46,786
- Last updated2000-12-01 v1
- Checksum2FA4A2CFA8701285
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000003 EMBL· GenBank· DDBJ | BAB13019.1 EMBL· GenBank· DDBJ | Genomic DNA |