P57367 · TRPD_BUCAI

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site795-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site79anthranilate 1 (UniProtKB | ChEBI)
Binding site82-835-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site875-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site89-925-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site91Mg2+ 1 (UniProtKB | ChEBI)
Binding site107-1155-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site110anthranilate 1 (UniProtKB | ChEBI)
Binding site1195-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site165anthranilate 2 (UniProtKB | ChEBI)
Binding site223Mg2+ 2 (UniProtKB | ChEBI)
Binding site224Mg2+ 1 (UniProtKB | ChEBI)
Binding site224Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • Ordered locus names
      BU280

Organism names

Accessions

  • Primary accession
    P57367

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001544341-342Anthranilate phosphoribosyltransferase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    342
  • Mass (Da)
    38,756
  • Last updated
    2000-12-01 v1
  • Checksum
    9258AE148596CC24
MRNILLKIYDSKFLNQEESYQLFTLISSGKITDIKLASILTAMKIRGESIEEITGAIKAFLDKMKYFPKPDYIFSDIVGTGGDAKNTINISTMSAFVAATCGLKIIKHCNQRISSKSGSSDILEKFNINLNASPEKSRKTLDQLNICFLFAPKYHDGFKYSNNVRTDLKTKTIFNFLGPFLNPATPPLSVIGVYNKNLINIAVNILKNLQYKRAIVLHSDNTDEVTLYGTTYVSELLNKKIISYQLQPESFGLKMHPKKILKINSLEENYHIIKEIMKGKGSKLYEELIAVNVAMLLKVFGYENLKENTKLALNKIRSGDVYKHIRNVANMLKEDNHARHNT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000003
EMBL· GenBank· DDBJ
BAB12990.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp