P55852 · SUMO1_ARATH

Function

function

Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Required for the massive protein sumoylation in the nucleus induced by heat shock and controlled by SIZ1. Involved in the regulation of the heat stress transcription factor HSFA2 in acquired thermotolerance.

Miscellaneous

Stress conditions rapidly and substantially elevates the amount of SUMO1 and SUMO2 conjugates with a concomitant reduction in the amount of free SUMO proteins. The SUMO conjugation system plays an important function in stress protection and/or repair.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentnucleus
Molecular Functionprotein tag activity
Biological Processheat acclimation
Biological Processnegative regulation of DNA-binding transcription factor activity
Biological Processprotein sumoylation
Biological Processresponse to heat

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Small ubiquitin-related modifier 1
  • Short names
    AtSUMO1
  • Alternative names
    • Ubiquitin-like protein SMT3

Gene names

    • Name
      SUMO1
    • Synonyms
      SMT3
      , SUM1
    • ORF names
      F10M23.180
    • Ordered locus names
      At4g26840

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    P55852
  • Secondary accessions
    • Q547B9
    • Q9SZ24

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

No visible phenotype.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 3 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, cross-link.

TypeIDPosition(s)Description
ChainPRO_00001148911-100
Cross-link93Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Interacts with SAE2, SCE1, SIZ1 and MMS21 (By similarity).
Interacts with HSFA2 (PubMed:20521085).
Covalently attached to ABI5, FLD, GTE3, HSFA2 and ICE1 (PubMed:20521085).

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P55852ABI5 Q9SJN02EBI-15763381, EBI-1778690

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Region1-21Disordered
Domain16-93Ubiquitin-like

Sequence similarities

Belongs to the ubiquitin family. SUMO subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    100
  • Mass (Da)
    10,976
  • Last updated
    2002-06-20 v2
  • Checksum
    6F1E8721E7734A4A
MSANQEEDKKPGDGGAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVDMNSIAFLFDGRRLRAEQTPDELDMEDGDEIDAMLHQTGGSGGGATA

Sequence caution

The sequence CAA67923.1 differs from that shown. Reason: Miscellaneous discrepancy Sequencing errors.

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X99609
EMBL· GenBank· DDBJ
CAA67923.1
EMBL· GenBank· DDBJ
mRNA Sequence problems.
AF510519
EMBL· GenBank· DDBJ
AAN03845.1
EMBL· GenBank· DDBJ
mRNA
AL035440
EMBL· GenBank· DDBJ
CAB36530.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161565
EMBL· GenBank· DDBJ
CAB79539.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE85259.1
EMBL· GenBank· DDBJ
Genomic DNA
AY072368
EMBL· GenBank· DDBJ
AAL62360.1
EMBL· GenBank· DDBJ
mRNA
BT008437
EMBL· GenBank· DDBJ
AAP37796.1
EMBL· GenBank· DDBJ
mRNA
AY086914
EMBL· GenBank· DDBJ
AAM64478.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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