P55852 · SUMO1_ARATH
- ProteinSmall ubiquitin-related modifier 1
- GeneSUMO1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids100 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Required for the massive protein sumoylation in the nucleus induced by heat shock and controlled by SIZ1. Involved in the regulation of the heat stress transcription factor HSFA2 in acquired thermotolerance.
Miscellaneous
Stress conditions rapidly and substantially elevates the amount of SUMO1 and SUMO2 conjugates with a concomitant reduction in the amount of free SUMO proteins. The SUMO conjugation system plays an important function in stress protection and/or repair.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Molecular Function | protein tag activity | |
Biological Process | heat acclimation | |
Biological Process | negative regulation of DNA-binding transcription factor activity | |
Biological Process | protein sumoylation | |
Biological Process | response to heat |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSmall ubiquitin-related modifier 1
- Short namesAtSUMO1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionP55852
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Phenotypes & Variants
Disruption phenotype
No visible phenotype.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 3 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000114891 | 1-100 | Small ubiquitin-related modifier 1 | |||
Sequence: MSANQEEDKKPGDGGAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVDMNSIAFLFDGRRLRAEQTPDELDMEDGDEIDAMLHQTGGSGGGATA | ||||||
Cross-link | 93 | Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) | ||||
Sequence: G |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Interacts with SAE2, SCE1, SIZ1 and MMS21 (By similarity).
Interacts with HSFA2 (PubMed:20521085).
Covalently attached to ABI5, FLD, GTE3, HSFA2 and ICE1 (PubMed:20521085).
Interacts with HSFA2 (PubMed:20521085).
Covalently attached to ABI5, FLD, GTE3, HSFA2 and ICE1 (PubMed:20521085).
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | P55852 | ABI5 Q9SJN0 | 2 | EBI-15763381, EBI-1778690 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | ||||
Sequence: MSANQEEDKKPGDGGA | ||||||
Region | 1-21 | Disordered | ||||
Sequence: MSANQEEDKKPGDGGAHINLK | ||||||
Domain | 16-93 | Ubiquitin-like | ||||
Sequence: AHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVDMNSIAFLFDGRRLRAEQTPDELDMEDGDEIDAMLHQTGG |
Sequence similarities
Belongs to the ubiquitin family. SUMO subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length100
- Mass (Da)10,976
- Last updated2002-06-20 v2
- Checksum6F1E8721E7734A4A
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | ||||
Sequence: MSANQEEDKKPGDGGA |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X99609 EMBL· GenBank· DDBJ | CAA67923.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. | |
AF510519 EMBL· GenBank· DDBJ | AAN03845.1 EMBL· GenBank· DDBJ | mRNA | ||
AL035440 EMBL· GenBank· DDBJ | CAB36530.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL161565 EMBL· GenBank· DDBJ | CAB79539.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE85259.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY072368 EMBL· GenBank· DDBJ | AAL62360.1 EMBL· GenBank· DDBJ | mRNA | ||
BT008437 EMBL· GenBank· DDBJ | AAP37796.1 EMBL· GenBank· DDBJ | mRNA | ||
AY086914 EMBL· GenBank· DDBJ | AAM64478.1 EMBL· GenBank· DDBJ | mRNA |