The MEL gene: a new member of the RAB/YPT class of RAS-related genes.Nimmo E.R., Sanders P.G., Padua R.A., Hughes D., Williamson R., Johnson K.J.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCOncogene 6:1347-1351 (1991)Cited in2Mapped to2
The transcriptional landscape of the mammalian genome.Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6JTissueCerebellum, RetinaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 309:1559-1563 (2005)Cited in99+16Mapped to99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainFVB/NTissueLiverCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
No title available.Lubec G., Kang S.U.Cited forPROTEIN SEQUENCE OF 11-21; 59-69 AND 139-153, IDENTIFICATION BY MASS SPECTROMETRYStrainC57BL/6JTissueBrainCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to UniProtKB (APR-2007)Cited in99+
In its active form, the GTP-binding protein rab8 interacts with a stress- activated protein kinase.Ren M., Zeng J., De Lemos-Chiarandini C., Rosenfeld M., Adesnik M., Sabatini D.D.View abstractCited forINTERACTION WITH MAP4K2StrainBALB/cJTissueMelanomaCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 93:5151-5155 (1996)Cited in2Mapped to11
Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.Fukuda M.View abstractCited forINTERACTION WITH RIMS2; RPH3A AND RPH3ALCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 278:15373-15380 (2003)Cited in1351Mapped to42
Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.Fukuda M.View abstractCited forINTERACTION WITH SYTL4CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 278:15390-15396 (2003)Cited in6Mapped to51
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.Yang H., Sasaki T., Minoshima S., Shimizu N.View abstractCited forINTERACTION WITH SGSM1 AND SGSM3CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenomics 90:249-260 (2007)Cited in15Mapped to21
The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.Yamamura R., Nishimura N., Nakatsuji H., Arase S., Sasaki T.View abstractCited forFUNCTION IN ENDOCYTIC RECYCLING, SUBCELLULAR LOCATION, INTERACTION WITH MICAL1; MICALL1 AND MICALL2CategoriesFunction, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Biol. Cell 19:971-983 (2008)Cited in6Mapped to21
Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking.Hsiao Y.C., Tong Z.J., Westfall J.E., Ault J.G., Page-McCaw P.S., Ferland R.J.View abstractCited forSUBCELLULAR LOCATION, INTERACTION WITH AHI1CategoriesInteraction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mol. Genet. 18:3926-3941 (2009)Cited in2Mapped to26
The phagosomal proteome in interferon-gamma-activated macrophages.Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCImmunity 30:143-154 (2009)Cited in99+99+Mapped to99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-185, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueBrain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas, Spleen, TestisCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Pitchfork regulates primary cilia disassembly and left-right asymmetry.Kinzel D., Boldt K., Davis E.E., Burtscher I., Trumbach D., Diplas B., Attie-Bitach T., Wurst W., Katsanis N.[...], Lickert H.View abstractCited forINTERACTION WITH CIMAP3CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDev. Cell 19:66-77 (2010)Cited in18Mapped to45
The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis.Kypri E., Christodoulou A., Maimaris G., Lethan M., Markaki M., Lysandrou C., Lederer C.W., Tavernarakis N., Geimer S.[...], Santama N.View abstractCited forSUBCELLULAR LOCATIONCategoriesSubcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell. Mol. Life Sci. 71:517-538 (2014)Cited in11Mapped to2
GSK3beta-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis.Zhang B., Zhang T., Wang G., Wang G., Chi W., Jiang Q., Zhang C.View abstractCited forFUNCTION, INTERACTION WITH DZIP1, SUBCELLULAR LOCATIONCategoriesFunction, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS Biol. 13:e1002129-e1002129 (2015)Cited in6Mapped to19
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.Steger M., Tonelli F., Ito G., Davies P., Trost M., Vetter M., Wachter S., Lorentzen E., Duddy G.[...], Mann M.View abstractCited forPHOSPHORYLATION AT THR-72CategoriesPTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 5:0-0 (2016)Cited in18Mapped to6
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.Steger M., Diez F., Dhekne H.S., Lis P., Nirujogi R.S., Karayel O., Tonelli F., Martinez T.N., Lorentzen E.[...], Mann M.View abstractCited forINTERACTION WITH RILPL1 AND RILPL2, PHOSPHORYLATION AT THR-72CategoriesPTM / Processing, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 6:0-0 (2017)Cited in33Mapped to6
LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis.Eguchi T., Kuwahara T., Sakurai M., Komori T., Fujimoto T., Ito G., Yoshimura S.I., Harada A., Fukuda M.[...], Iwatsubo T.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, PHOSPHORYLATION AT THR-72CategoriesFunction, PTM / Processing, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 115:E9115-E9124 (2018)Cited in6Mapped to4
Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.Itzen A., Pylypenko O., Goody R.S., Alexandrov K., Rak A.View abstractCited forX-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 1-175 IN COMPLEX WITH RABIF, INTERACTION WITH RABIF, CATALYTIC ACTIVITYCategoriesFunction, Interaction, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 25:1445-1455 (2006)Cited in2Mapped to1
Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors.Ishikawa T.O., Tamai Y., Rochelle J.M., Hirata M., Namba T., Sugimoto Y., Ichikawa A., Narumiya S., Taketo M.M., Seldin M.F.View abstractCategoriesSequencesSourceMGI: 96960PubMedEurope PMCGenomics 32:285-288 (1996)Mapped to58
Mouse Sin3A interacts with and can functionally substitute for the amino- terminal repression of the Myc antagonist Mxi1.Rao G., Alland L., Guida P., Schreiber-Agus N., Chin L., Chen K., Rochelle J.M., Seldin M.F., Skoultchi A.I., DePinho R.A.View abstractCategoriesInteractionSourceMGI: 96960PubMedEurope PMCOncogene 12:1165-1172 (1996)Cited in1Mapped to54
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 96960PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.Wu J., Moriwaki K., Asuka T., Nakai R., Kanda S., Taniguchi M., Sugiyama T., Yoshimura S.I., Kunii M.[...], Harada A.View abstractSourceMGI: 96960PubMedEurope PMCBlood Adv 7:3382-3394 (2023)Mapped to74
Rab8A promotes breast cancer progression by increasing surface expression of Tropomyosin-related kinase B.Liu Y., Zhang Z., Gao X., Ma Q., Yu Z., Huang S.View abstractAnnotationRab8A promotes breast cancer progression by increasing surface expression of Tropomyosin-related kinase B.CategoriesFunction, InteractionSourceGeneRif: 17274PubMedEurope PMCCancer Lett 535:215629-215629 (2022)Mapped to10
Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes.Stypulkowski E., Feng Q., Joseph I., Farrell V., Flores J., Yu S., Sakamori R., Sun J., Bandyopadhyay S.[...], Gao N.View abstractAnnotationRab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes.CategoriesFunction, Subcellular LocationSourceGeneRif: 17274, MGI: 96960PubMedEurope PMCJ Biol Chem 296:100488-100488 (2021)Mapped to3