P54928 · IMP3_SOLLC
- ProteinInositol monophosphatase 3
- GeneIMP3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids268 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides.
Catalytic activity
- a myo-inositol phosphate + H2O = myo-inositol + phosphate
Cofactor
Pathway
Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 71 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 71 | substrate | ||||
Sequence: E | ||||||
Binding site | 91 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 91 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 93 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 93-96 | substrate | ||||
Sequence: LDGT | ||||||
Binding site | 94 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 194-196 | substrate | ||||
Sequence: GSC | ||||||
Binding site | 213 | substrate | ||||
Sequence: E | ||||||
Binding site | 221 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 221 | substrate | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | inositol monophosphate 1-phosphatase activity | |
Molecular Function | inositol monophosphate 3-phosphatase activity | |
Molecular Function | inositol monophosphate 4-phosphatase activity | |
Molecular Function | inositol monophosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | inositol biosynthetic process | |
Biological Process | inositol metabolic process | |
Biological Process | phosphatidylinositol phosphate biosynthetic process | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameInositol monophosphatase 3
- EC number
- Short namesIMP 3; IMPase 3; LeIMP3
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Solanoideae > Solaneae > Solanum > Solanum subgen. Lycopersicon
Accessions
- Primary accessionP54928
Proteomes
Genome annotation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000142525 | 1-268 | Inositol monophosphatase 3 | |||
Sequence: MAQNGSVEQFLDVAVEAAKKAGEIIREGFYKTKHVEHKGMVDLVTETDKACEDFIFNHLKQRFPSHKFIGEETTAACGNFELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIEKKPTVGVVYNPIIDELFTGIDGKGAFLNGKPIKVSSQSELVKALLATEAGTNRDKLVVDATTGRINSLLFKVRSLRMCGSCALNLCGVACGRLDLFYELEFGGPWDVAGGAVIVKEAGGFVFDPSGSEFDLTARRVAATNAHLKDAFIKALNE |
Proteomic databases
Expression
Tissue specificity
Expressed in the shoot apex, roots, stems, leaves, flowers and young and mature green fruits.
Induction
Up-regulated by light and down-regulated by Li+.
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length268
- Mass (Da)29,054
- Last updated1996-10-01 v1
- ChecksumBCB635A029804901
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U39059 EMBL· GenBank· DDBJ | AAB19031.1 EMBL· GenBank· DDBJ | mRNA | ||
AEKE02005274 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |