P54784 · ORC1_YEAST
- ProteinOrigin recognition complex subunit 1
- GeneORC1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids914 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
s13-142702 | 165 | V>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.54) Somatic: No Accession: XIII:g.142702G>A Codon: GTC/ATC Consequence type: missense Cytogenetic band: Genomic location: XIII:g.142702G>A Locations: - p.Val165Ile (Ensembl:YML065W_mRNA) - c.493G>A (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-142702 | |||||||
s13-142831 | 208 | L>M | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.03) Somatic: No Accession: XIII:g.142831T>A Codon: TTG/ATG Consequence type: missense Cytogenetic band: Genomic location: XIII:g.142831T>A Locations: - p.Leu208Met (Ensembl:YML065W_mRNA) - c.622T>A (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-142831 | |||||||
s13-142984 | 259 | D>N | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.19) Somatic: No Accession: XIII:g.142984G>A Codon: GAT/AAT Consequence type: missense Cytogenetic band: Genomic location: XIII:g.142984G>A Locations: - p.Asp259Asn (Ensembl:YML065W_mRNA) - c.775G>A (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-142984 | |||||||
s13-143064 | 285 | E>D | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: XIII:g.143064A>C Codon: GAA/GAC Consequence type: missense Cytogenetic band: Genomic location: XIII:g.143064A>C Locations: - p.Glu285Asp (Ensembl:YML065W_mRNA) - c.855A>C (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-143064 | |||||||
s13-143070 | 287 | D>E | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.42) Somatic: No Accession: XIII:g.143070C>A Codon: GAC/GAA Consequence type: missense Cytogenetic band: Genomic location: XIII:g.143070C>A Locations: - p.Asp287Glu (Ensembl:YML065W_mRNA) - c.861C>A (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-143070 | |||||||
s13-143134 | 309 | G>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.53) Somatic: No Accession: XIII:g.143134G>C Codon: GGC/CGC Consequence type: missense Cytogenetic band: Genomic location: XIII:g.143134G>C Locations: - p.Gly309Arg (Ensembl:YML065W_mRNA) - c.925G>C (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-143134 | |||||||
s13-143141 | 311 | K>T | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.64) Somatic: No Accession: XIII:g.143141A>C Codon: AAG/ACG Consequence type: missense Cytogenetic band: Genomic location: XIII:g.143141A>C Locations: - p.Lys311Thr (Ensembl:YML065W_mRNA) - c.932A>C (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-143141 | |||||||
s13-143356 | 383 | A>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.71) Somatic: No Accession: XIII:g.143356G>T Codon: GCT/TCT Consequence type: missense Cytogenetic band: Genomic location: XIII:g.143356G>T Locations: - p.Ala383Ser (Ensembl:YML065W_mRNA) - c.1147G>T (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-143356 | |||||||
s13-143587 | 460 | Y>H | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: XIII:g.143587T>C Codon: TAT/CAT Consequence type: missense Cytogenetic band: Genomic location: XIII:g.143587T>C Locations: - p.Tyr460His (Ensembl:YML065W_mRNA) - c.1378T>C (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-143587 | |||||||
s13-144203 | 665 | N>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.58) Somatic: No Accession: XIII:g.144203A>G Codon: AAC/AGC Consequence type: missense Cytogenetic band: Genomic location: XIII:g.144203A>G Locations: - p.Asn665Ser (Ensembl:YML065W_mRNA) - c.1994A>G (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-144203 | |||||||
s13-144245 | 679 | K>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.24) Somatic: No Accession: XIII:g.144245A>G Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: XIII:g.144245A>G Locations: - p.Lys679Arg (Ensembl:YML065W_mRNA) - c.2036A>G (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-144245 | |||||||
s13-144403 | 732 | K>E | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.7) Somatic: No Accession: XIII:g.144403A>G Codon: AAG/GAG Consequence type: missense Cytogenetic band: Genomic location: XIII:g.144403A>G Locations: - p.Lys732Glu (Ensembl:YML065W_mRNA) - c.2194A>G (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-144403 | |||||||
s13-144479 | 757 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.4) Somatic: No Accession: XIII:g.144479C>T Codon: GCC/GTC Consequence type: missense Cytogenetic band: Genomic location: XIII:g.144479C>T Locations: - p.Ala757Val (Ensembl:YML065W_mRNA) - c.2270C>T (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-144479 | |||||||
s13-144518 | 770 | V>A | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.16) Somatic: No Accession: XIII:g.144518T>C Codon: GTA/GCA Consequence type: missense Cytogenetic band: Genomic location: XIII:g.144518T>C Locations: - p.Val770Ala (Ensembl:YML065W_mRNA) - c.2309T>C (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-144518 | |||||||
s13-144592 | 795 | T>A | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.42) Somatic: No Accession: XIII:g.144592A>G Codon: ACG/GCG Consequence type: missense Cytogenetic band: Genomic location: XIII:g.144592A>G Locations: - p.Thr795Ala (Ensembl:YML065W_mRNA) - c.2383A>G (Ensembl:YML065W_mRNA) Source type: large scale study Cross-references: - SGRP: s13-144592 |