P53894 · CBK1_YEAST
- ProteinSerine/threonine-protein kinase CBK1
- GeneCBK1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids756 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
Miscellaneous
Present with 450 molecules/cell in log phase SD medium.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell cortex | |
Cellular Component | cellular bud | |
Cellular Component | cellular bud neck | |
Cellular Component | cellular bud tip | |
Cellular Component | cytoplasm | |
Cellular Component | cytoplasmic stress granule | |
Cellular Component | incipient cellular bud site | |
Cellular Component | mating projection tip | |
Cellular Component | nucleus | |
Cellular Component | prospore membrane | |
Cellular Component | serine/threonine protein kinase complex | |
Molecular Function | ATP binding | |
Molecular Function | identical protein binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | budding cell apical bud growth | |
Biological Process | establishment or maintenance of actin cytoskeleton polarity | |
Biological Process | establishment or maintenance of cell polarity | |
Biological Process | intracellular signal transduction | |
Biological Process | regulation of fungal-type cell wall organization | |
Biological Process | regulation of protein secretion | |
Biological Process | septum digestion after cytokinesis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase CBK1
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionP53894
- Secondary accessions
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000085697 | 1-756 | Serine/threonine-protein kinase CBK1 | |||
Sequence: MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQIPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQQEQENVQVQQQLSQAQQQNSRQQQQQLQYQQQQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFDYLTRKNAL | ||||||
Modified residue | 109 | Phosphothreonine | ||||
Sequence: T |
Keywords
- PTM
Proteomic databases
PTM databases
Interaction
Subunit
Associates with PAG1/TAO3 and interacts with MOB2.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | P53894 | ACE2 P21192 | 3 | EBI-4110, EBI-2073 | |
BINARY | P53894 | CBK1 P53894 | 3 | EBI-4110, EBI-4110 | |
BINARY | P53894 | CDC14 Q00684 | 5 | EBI-4110, EBI-4192 | |
BINARY | P53894 | MOB2 P43563 | 8 | EBI-4110, EBI-11125 | |
BINARY | P53894 | SSD1 P24276 | 4 | EBI-4110, EBI-18153 | |
BINARY | P53894 | TAO3 P40468 | 9 | EBI-4110, EBI-18961 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-41 | Polar residues | ||||
Sequence: MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNP | ||||||
Region | 1-180 | Disordered | ||||
Sequence: MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQIPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSS | ||||||
Compositional bias | 56-79 | Polar residues | ||||
Sequence: NYMKEQGSHQSLQEHLQRETGNLG | ||||||
Compositional bias | 96-180 | Polar residues | ||||
Sequence: PHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSS | ||||||
Region | 242-261 | Disordered | ||||
Sequence: QQQQQQQSQSPVQSGFNNGT | ||||||
Domain | 352-672 | Protein kinase | ||||
Sequence: FHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFF | ||||||
Domain | 673-754 | AGC-kinase C-terminal | ||||
Sequence: RGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFDYLTRKN | ||||||
Region | 707-732 | Disordered | ||||
Sequence: NVPDSPAMAQAAKQREQMTKQGGSAP |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length756
- Mass (Da)86,946
- Last updated1996-10-01 v1
- Checksum87EBCD2C3C96EE11
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-41 | Polar residues | ||||
Sequence: MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNP | ||||||
Compositional bias | 56-79 | Polar residues | ||||
Sequence: NYMKEQGSHQSLQEHLQRETGNLG | ||||||
Compositional bias | 96-180 | Polar residues | ||||
Sequence: PHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X92517 EMBL· GenBank· DDBJ | CAA63278.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z71437 EMBL· GenBank· DDBJ | CAA96048.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006947 EMBL· GenBank· DDBJ | DAA10388.1 EMBL· GenBank· DDBJ | Genomic DNA |