P53353 · ASPX_VULVU
- ProteinSperm acrosomal protein FSA-ACR.1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids349 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | acrosomal vesicle |
Names & Taxonomy
Protein names
- Recommended nameSperm acrosomal protein FSA-ACR.1
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Laurasiatheria > Carnivora (carnivores) > Caniformia > Canidae (dog, coyote, wolf, fox) > Vulpes
Accessions
- Primary accessionP53353
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: Intracellular acrosomal compartment of sperm.
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-8 | |||||
Sequence: MKEVYLVG | ||||||
Chain | PRO_0000020763 | 9-349 | Sperm acrosomal protein FSA-ACR.1 | |||
Sequence: YARGASGQSDEPPGSMDHQASVQRLSGEYFSLGNPSDGEALYETAAGENTLSEHTSGEHTSVEHASAEHSSTEHTSGEHASGEHTSGERATGEHTSSEHATSEHTSGEQPSGEQPSGEKSSGEQPSGEKSSGEQPSGEKSLGEQPSGEQSSGEKSSAEQTSGEQAVAEKPSGEHAVAEKPSGEQAVAERPSGEQAVAEKPLGEQAVAERPSGEQASIEKASSEQASAEQASAEQASSEQASGEKPLGEQPSGIPPSSTFSGPILNCHTCSYMNDQGKCLRGEGVCSTQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI | ||||||
Glycosylation | 342 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Expression
Tissue specificity
Testis.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-265 | Disordered | ||||
Sequence: MKEVYLVGYARGASGQSDEPPGSMDHQASVQRLSGEYFSLGNPSDGEALYETAAGENTLSEHTSGEHTSVEHASAEHSSTEHTSGEHASGEHTSGERATGEHTSSEHATSEHTSGEQPSGEQPSGEKSSGEQPSGEKSSGEQPSGEKSLGEQPSGEQSSGEKSSAEQTSGEQAVAEKPSGEHAVAEKPSGEQAVAERPSGEQAVAEKPLGEQAVAERPSGEQASIEKASSEQASAEQASAEQASSEQASGEKPLGEQPSGIPPSS | ||||||
Compositional bias | 20-38 | Polar residues | ||||
Sequence: PPGSMDHQASVQRLSGEYF | ||||||
Compositional bias | 65-109 | Basic and acidic residues | ||||
Sequence: GEHTSVEHASAEHSSTEHTSGEHASGEHTSGERATGEHTSSEHAT | ||||||
Compositional bias | 110-174 | Polar residues | ||||
Sequence: SEHTSGEQPSGEQPSGEKSSGEQPSGEKSSGEQPSGEKSLGEQPSGEQSSGEKSSAEQTSGEQAV | ||||||
Compositional bias | 223-252 | Polar residues | ||||
Sequence: ASIEKASSEQASAEQASAEQASSEQASGEK |
Sequence similarities
To acrosomal proteins SP-10.
Keywords
- Domain
Family and domain databases
Sequence & Isoforms
- Sequence statusFragment
- Sequence processingThe displayed sequence is further processed into a mature form.
This entry describes 3 isoforms produced by Alternative splicing. Experimental confirmation may be lacking for some isoforms.
P53353-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- SynonymsFSA-Acr.1
- Length349
- Mass (Da)36,486
- Last updated1996-10-01 v1
- Checksum10E762D86805BD83
P53353-2
- Name2
- SynonymsFSA-Acr.2
P53353-3
- Name3
- SynonymsFSA-Acr.3
- Differences from canonical
- 140-140: G → GEQPSGEKSLGEQPSGEKSSG
Features
Showing features for non-terminal residue, alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: M | ||||||
Alternative sequence | VSP_004130 | 1-7 | in isoform 2 | |||
Sequence: MKEVYLV → MSLYLI | ||||||
Compositional bias | 20-38 | Polar residues | ||||
Sequence: PPGSMDHQASVQRLSGEYF | ||||||
Compositional bias | 65-109 | Basic and acidic residues | ||||
Sequence: GEHTSVEHASAEHSSTEHTSGEHASGEHTSGERATGEHTSSEHAT | ||||||
Compositional bias | 110-174 | Polar residues | ||||
Sequence: SEHTSGEQPSGEQPSGEKSSGEQPSGEKSSGEQPSGEKSLGEQPSGEQSSGEKSSAEQTSGEQAV | ||||||
Alternative sequence | VSP_004131 | 140 | in isoform 2 | |||
Sequence: G → GEQPSGEKSSG | ||||||
Alternative sequence | VSP_004132 | 140 | in isoform 3 | |||
Sequence: G → GEQPSGEKSLGEQPSGEKSSG | ||||||
Compositional bias | 223-252 | Polar residues | ||||
Sequence: ASIEKASSEQASAEQASAEQASSEQASGEK |
Keywords
- Coding sequence diversity
- Technical term