P53142 · VPS73_YEAST
- ProteinVacuolar protein sorting-associated protein 73
- GeneVPS73
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids486 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
May be involved in vacuolar protein sorting.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | fungal-type vacuole membrane | |
Cellular Component | membrane | |
Cellular Component | mitochondrial membrane | |
Cellular Component | mitochondrion | |
Molecular Function | hexose transmembrane transporter activity | |
Molecular Function | transmembrane transporter activity | |
Biological Process | monosaccharide transmembrane transport | |
Biological Process | protein targeting to vacuole | |
Biological Process | transmembrane transport |
Keywords
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameVacuolar protein sorting-associated protein 73
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionP53142
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-26 | Cytoplasmic | ||||
Sequence: MNRILSSASLLSNVSMPRQNKHKITK | ||||||
Transmembrane | 27-47 | Helical; Name=1 | ||||
Sequence: ALCYAIIVASIGSIQFGYHLS | ||||||
Topological domain | 48-90 | Mitochondrial intermembrane | ||||
Sequence: ELNAPQQVLSCSEFDIPMEGYPYDRTWLGKRGYKQCIPLNDEQ | ||||||
Transmembrane | 91-111 | Helical; Name=2 | ||||
Sequence: IGIVTSVFCIGGILGSYFATS | ||||||
Topological domain | 112-119 | Cytoplasmic | ||||
Sequence: LANIYGRK | ||||||
Transmembrane | 120-140 | Helical; Name=3 | ||||
Sequence: FSSLINCTLNIVGSLIIFNSN | ||||||
Topological domain | 141-146 | Mitochondrial intermembrane | ||||
Sequence: SYRGLI | ||||||
Transmembrane | 147-167 | Helical; Name=4 | ||||
Sequence: IGRILVGISCGSLIVIIPLFI | ||||||
Topological domain | 168-178 | Cytoplasmic | ||||
Sequence: KEVAPSGWEGL | ||||||
Transmembrane | 179-199 | Helical; Name=5 | ||||
Sequence: LGSMTQICIRLGVLLTQGIAL | ||||||
Topological domain | 200-208 | Mitochondrial intermembrane | ||||
Sequence: PLTDSYRWR | ||||||
Transmembrane | 209-229 | Helical; Name=6 | ||||
Sequence: WILFGSFLIAVLNFFMWFIVD | ||||||
Topological domain | 230-305 | Cytoplasmic | ||||
Sequence: ESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNVKSRH | ||||||
Transmembrane | 306-326 | Helical; Name=7 | ||||
Sequence: VITVLLFGQQFCGINSIVLYG | ||||||
Topological domain | 327-342 | Mitochondrial intermembrane | ||||
Sequence: TKIISQLYPQHAIRIN | ||||||
Transmembrane | 343-363 | Helical; Name=8 | ||||
Sequence: FFISMVNVLVTILVSLLIHSL | ||||||
Topological domain | 364-366 | Cytoplasmic | ||||
Sequence: PRK | ||||||
Transmembrane | 367-387 | Helical; Name=9 | ||||
Sequence: PLLMTSTVLVSVTAFIMGIAM | ||||||
Topological domain | 388-396 | Mitochondrial intermembrane | ||||
Sequence: NHNKMNLLI | ||||||
Transmembrane | 397-417 | Helical; Name=10 | ||||
Sequence: VFSFIYMGVFTMGLNPLPFII | ||||||
Topological domain | 418-432 | Cytoplasmic | ||||
Sequence: MREVSKPQDMVLAQR | ||||||
Transmembrane | 433-453 | Helical; Name=11 | ||||
Sequence: YGTICNWVGTFIIAYTFPIIH | ||||||
Topological domain | 454 | Mitochondrial intermembrane | ||||
Sequence: D | ||||||
Transmembrane | 455-475 | Helical; Name=12 | ||||
Sequence: VLSGYVFIIFAIIACSISAFI | ||||||
Topological domain | 476-486 | Cytoplasmic | ||||
Sequence: WKKVPETKRSG |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000050462 | 1-486 | Vacuolar protein sorting-associated protein 73 | |||
Sequence: MNRILSSASLLSNVSMPRQNKHKITKALCYAIIVASIGSIQFGYHLSELNAPQQVLSCSEFDIPMEGYPYDRTWLGKRGYKQCIPLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSYRWRWILFGSFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLYGTKIISQLYPQHAIRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGIAMNHNKMNLLIVFSFIYMGVFTMGLNPLPFIIMREVSKPQDMVLAQRYGTICNWVGTFIIAYTFPIIHDVLSGYVFIIFAIIACSISAFIWKKVPETKRSG |
Proteomic databases
PTM databases
Structure
Sequence
- Sequence statusComplete
- Length486
- Mass (Da)54,331
- Last updated1996-10-01 v1
- ChecksumD924D9112516450D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Z72626 EMBL· GenBank· DDBJ | CAA96811.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z72625 EMBL· GenBank· DDBJ | CAA96810.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
X97644 EMBL· GenBank· DDBJ | CAA66249.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006941 EMBL· GenBank· DDBJ | DAA08003.1 EMBL· GenBank· DDBJ | Genomic DNA |