P52991 · KHSE_LACLC
- ProteinHomoserine kinase
- GenethrB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids296 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
Catalytic activity
- ATP + L-homoserine = ADP + H+ + O-phospho-L-homoserine
Pathway
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | homoserine kinase activity | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine kinase
- EC number
- Short namesHK; HSK
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus
Accessions
- Primary accessionP52991
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000156579 | 1-296 | Homoserine kinase | |||
Sequence: MKIIVPATSANLGAGFDSIGIAVNLYLTVEVLGESRDWKIDHDLGENIPTDERNLLLTTLSAVLEDKNVALSAKFHLKMTSEVPLARGLGSSSSVIIAGIELANQLAKLNLTSDEKLKLACEIEGHPDNVAPALLGNLVIASTVAGKTSHIVADFPSCALLAFVPDYELKTVESRKVLPNELTYKEAVAASSIANVLTASLLTNNLEVAGQMMEADRFHESYRASLIPELQLLREIGHEFGAYGTYLSGAGPTVMLLVPDDKLTLLTEKIMEKNLTGHLYPLKIDNKGLQVEESVF |
Structure
Sequence
- Sequence statusComplete
- Length296
- Mass (Da)31,893
- Last updated1996-10-01 v1
- Checksum1EFA018C4DA89620