P52421 · PUR2_VIGUN

  • Protein
    Phosphoribosylamine--glycine ligase
  • Gene
    PUR2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N1-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphoribosylamine-glycine ligase activity
Biological Process'de novo' IMP biosynthetic process
Biological Processpurine nucleobase biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoribosylamine--glycine ligase
  • EC number
  • Alternative names
    • Glycinamide ribonucleotide synthetase (GARS)
    • Phosphoribosylglycinamide synthetase

Gene names

    • Name
      PUR2

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Vita 3
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > indigoferoid/millettioid clade > Phaseoleae > Vigna

Accessions

  • Primary accession
    P52421

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001515181-311Phosphoribosylamine--glycine ligase

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-191ATP-grasp

Sequence similarities

Belongs to the GARS family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    311
  • Mass (Da)
    33,070
  • Last updated
    1996-10-01 v1
  • Checksum
    B0CA31A1E2FCB227
DPRVRKQYIQEQGAPIVIKADGLAAGKGVTVAMTLEEAYKAVDSMLVQGDFGSAGCRVIVEEFLEGEEASFFALVDGENAIPLESAQDHKRVGDGDTGPNTGGMGAYSPAPVLTKELQSIVMDSIIIPTVKGMSAEGSKFVGVLYAGLMIEKKSGMPKLIEYNVRFGDPECQVLMVRLESDLVQVLLAACRGELNGVSLKWSPGSAMVVVMASKGYPGSYQKGTVIENLEEAEAVAPGIKIFHAGTAFDSEGRFIATGGRVLGVTAKGNDLEEACDRAYLAVENVNWPGGFLPSGYWLESSTSETSMLERE

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U30896
EMBL· GenBank· DDBJ
AAA74447.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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