The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton.Helliwell S.B., Schmidt A., Ohya Y., Hall M.N.View abstractAnnotationStrains/Constructs|Regulatory Role|Mutants/Phenotypes|Primary Literature|Function/ProcessCategoryFunctionSourceSGD: S000004363PubMedEurope PMCCurr Biol 8:1211-1214 (1998)Mapped to8
A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene.Jacoby J.J., Nilius S.M., Heinisch J.J.View abstractAnnotationGenetic Interactions|Strains/Constructs|Primary Literature|Function/ProcessCategoriesFunction, Phenotypes & VariantsSourceSGD: S000004363PubMedEurope PMCMol. Gen. Genet. 258:148-155 (1998)Cited in1Mapped to3
Cell wall integrity modulates RHO1 activity via the exchange factor ROM2.Bickle M., Delley P.-A., Schmidt A., Hall M.N.View abstractAnnotationCellular Location|Primary Literature|Function/ProcessCategoryFunctionSourceSGD: S000004363PubMedEurope PMCEMBO J. 17:2235-2245 (1998)Cited in2Mapped to3
The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae.Manning B.D., Padmanabha R., Snyder M.View abstractAnnotationGenetic Interactions|Strains/Constructs|Cellular Location|Mutants/Phenotypes|Primary Literature|Function/ProcessCategoryFunctionSourceSGD: S000004363PubMedEurope PMCMol. Biol. Cell 8:1829-1844 (1997)Cited in1Mapped to4
The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.Schmidt A., Bickle M., Beck T., Hall M.N.View abstractAnnotationGenetic Interactions|Strains/Constructs|Mutants/Phenotypes|Protein Sequence Features|Primary Literature|Function/ProcessCategoryFunctionSourceSGD: S000004363PubMedEurope PMCCell 88:531-542 (1997)Cited in3Mapped to5
Different Regulations of <i>ROM2</i> and <i>LRG1</i> Expression by Ccr4, Pop2, and Dhh1 in the <i>Saccharomyces cerevisiae</i> Cell Wall Integrity Pathway.Li X., Ohmori T., Irie K., Kimura Y., Suda Y., Mizuno T., Irie K.View abstractAnnotationS000004363CategoryFunctionSourceSGD: S000004363PubMedEurope PMCmSphere 1:e00250-16 (2016)Mapped to8
Signaling pathways coordinating the alkaline pH response confer resistance to the hevein-type plant antimicrobial peptide Pn-AMP1 in Saccharomyces cerevisiae.Kwon Y., Chiang J., Tran G., Giaever G., Nislow C., Hahn B.S., Kwak Y.S., Koo J.C.View abstractAnnotationPrimary LiteratureCategoriesFunction, Phenotypes & VariantsSourceSGD: S000004363PubMedEurope PMCPlanta 244:1229-1240 (2016)Mapped to4
Direct interaction of Ste11 and Mkk1/2 through Nst1 integrates high- osmolarity glycerol and pheromone pathways to the cell wall integrity MAPK pathway.Leng G., Song K.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCFEBS Lett 590:148-160 (2016)Mapped to11
alpha-Arrestins participate in cargo selection for both clathrin- independent and clathrin-mediated endocytosis.Prosser D.C., Pannunzio A.E., Brodsky J.L., Thorner J., Wendland B., O'Donnell A.F.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCJ Cell Sci 128:4220-4234 (2015)Mapped to11
Advantages and Challenges of Phenotypic Screens: The Identification of Two Novel Antifungal Geranylgeranyltransferase I Inhibitors.Pries V., Cotesta S., Riedl R., Aust T., Schuierer S., Tao J., Filipuzzi I., Hoepfner D.View abstractAnnotationPrimary LiteratureCategoriesFunction, Phenotypes & VariantsSourceSGD: S000004363PubMedEurope PMCJ Biomol Screen 21:306-315 (2016)Mapped to7
A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.McCormick M.A., Delaney J.R., Tsuchiya M., Tsuchiyama S., Shemorry A., Sim S., Chou A.C., Ahmed U., Carr D.[...], Kennedy B.K.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCCell Metab 22:895-906 (2015)Mapped to99+
The yeast cell wall integrity pathway signals from recycling endosomes upon elimination of phosphatidylinositol (4,5)-bisphosphate by mammalian phosphatidylinositol 3-kinase.Fernandez-Acero T., Rodriguez-Escudero I., Molina M., Cid V.J.View abstractAnnotationPrimary LiteratureCategoriesFunction, Subcellular LocationSourceSGD: S000004363PubMedEurope PMCCell Signal 27:2272-2284 (2015)Mapped to3
Cell biology of yeast zygotes, from genesis to budding.Tartakoff A.M.View abstractAnnotationReviewsCategoryFunctionSourceSGD: S000004363PubMedEurope PMCBiochim Biophys Acta 1853:1702-1714 (2015)Mapped to27
Plant-derived antifungal agent poacic acid targets beta-1,3-glucan.Piotrowski J.S., Okada H., Lu F., Li S.C., Hinchman L., Ranjan A., Smith D.L., Higbee A.J., Ulbrich A.[...], Ohya Y.View abstractAnnotationS000004363CategoryFunctionSourceSGD: S000004363PubMedEurope PMCProc Natl Acad Sci U S A 112:E1490-7 (2015)Mapped to19
Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids.Olson D.K., Frohlich F., Christiano R., Hannibal-Bach H.K., Ejsing C.S., Walther T.C.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCJ Biol Chem 290:4238-4247 (2015)Mapped to1
The budding yeast amphiphysin complex is required for contractile actin ring (CAR) assembly and post-contraction GEF-independent accumulation of Rho1-GTP.Cundell M.J., Price C.View abstractAnnotationS000004363CategoryFunctionSourceSGD: S000004363PubMedEurope PMCPLoS One 9:e97663-e97663 (2014)Mapped to6
Therapeutic modulation of eIF2alpha phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.Kim H.J., Raphael A.R., LaDow E.S., McGurk L., Weber R.A., Trojanowski J.Q., Lee V.M., Finkbeiner S., Gitler A.D., Bonini N.M.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCNat Genet 46:152-160 (2014)Mapped to58
The Wsc1p cell wall signaling protein controls biofilm (Mat) formation independently of Flo11p in Saccharomyces cerevisiae.Sarode N., Davis S.E., Tams R.N., Reynolds T.B.View abstractAnnotationS000004363CategoryFunctionSourceSGD: S000004363PubMedEurope PMCG3 (Bethesda) 4:199-207 (2014)Mapped to14
Actin - a biosensor that determines cell fate in yeasts.Smethurst D.G., Dawes I.W., Gourlay C.W.View abstractAnnotationReviewsCategoryFunctionSourceSGD: S000004363PubMedEurope PMCFEMS Yeast Res 14:89-95 (2014)Mapped to22
Functional genomics indicates yeast requires Golgi/ER transport, chromatin remodeling, and DNA repair for low dose DMSO tolerance.Gaytan B.D., Loguinov A.V., De La Rosa V.Y., Lerot J.M., Vulpe C.D.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCFront Genet 4:154-154 (2013)Mapped to44
Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis.Onishi M., Ko N., Nishihama R., Pringle J.R.View abstractAnnotationPrimary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCJ Cell Biol 202:311-329 (2013)Mapped to8
Conserved roles for yeast Rho1 and mammalian RhoA GTPases in clathrin- independent endocytosis.Prosser D.C., Wendland B.View abstractAnnotationReviewsCategoryFunctionSourceSGD: S000004363PubMedEurope PMCSmall GTPases 3:229-235 (2012)Mapped to12
Identification of new cell size control genes in S. cerevisiae.Dungrawala H., Hua H., Wright J., Abraham L., Kasemsri T., McDowell A., Stilwell J., Schneider B.L.View abstractAnnotationPrimary LiteratureCategoriesFunction, SequencesSourceSGD: S000004363PubMedEurope PMCCell Div 7:24-24 (2012)Mapped to11
Vesicle trafficking from a lipid perspective: Lipid regulation of exocytosis in Saccharomyces cerevisiae.Johansen J., Ramanathan V., Beh C.T.View abstractAnnotationReviewsCategoryFunctionSourceSGD: S000004363PubMedEurope PMCCell Logist 2:151-160 (2012)Mapped to59
The high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM-1.Miyamoto M., Furuichi Y., Komiyama T.View abstractAnnotationStrains/Constructs|Mutants/Phenotypes|Primary LiteratureCategoryFunctionSourceSGD: S000004363PubMedEurope PMCYeast 29:475-485 (2012)Mapped to21