Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase).Tassan J.-P., Schultz S.J., Bartek J., Nigg E.A.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]TissuePlacentaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Cell Biol. 127:467-478 (1994)Cited in1Mapped to1
Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern.Levedakou E.N., He M., Baptist E.W., Craven R.J., Cance W.G., Welcsh P.L., Simmons A., Naylor S.L., Leach R.J.[...], Liu E.T.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]TissueMammary glandCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCOncogene 9:1977-1988 (1994)Cited in2
Cloning, expression and subcellular localization of the human homolog of p40MO15 catalytic subunit of cdk-activating kinase.Darbon J.-M., Devault A., Taviaux S., Fesquet D., Martinez A.-M., Galas S., Cavadore J.-C., Doree M., Blanchard J.-M.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCOncogene 9:3127-3138 (1994)Cited in1
Molecular cloning of the human CAK1 gene encoding a cyclin-dependent kinase-activating kinase.Wu L., Yee A., Liu L., Carbonaro-Hall D., Venkatesan N., Tolo T., Hall F.L.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]TissueFibroblastCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCOncogene 9:2089-2096 (1994)Cited in11
Human and Xenopus MO15 mRNA are highly conserved but show different patterns of expression in adult tissues.Kobelt D., Karn T., Hock B., Holtrich U., Braeuninger A., Wolf G., Strebhardt K., Ruebsamen-Waigmann H.Cited forNUCLEOTIDE SEQUENCE [MRNA]TissueLung, ThymusCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Oncol. Rep. 1:1269-1275 (1994)Cited in1
No title available.NIEHS SNPs programCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS ALA-163 AND MET-285CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUL-2002)Cited in20
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueCervix, Urinary bladderCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase.Fisher R.P., Morgan D.O.View abstractCited forMUTAGENESIS OF THR-170CategoriesDisease & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 78:713-724 (1994)Cited in2
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.Ko L.J., Shieh S.-Y., Chen X., Jayaraman L., Tamai K., Taya Y., Prives C., Pan Z.-Q.View abstractCited forFUNCTION AS TP53 KINASECategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 17:7220-7229 (1997)Cited in2
The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7.Akoulitchev S., Reinberg D.View abstractCited forPHOSPHORYLATION AT SER-164 AND THR-170, MUTAGENESIS OF SER-164 AND THR-170CategoriesPTM / Processing, Disease & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenes Dev. 12:3541-3550 (1998)Cited in1
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.Kershnar E., Wu S.-Y., Chiang C.-M.View abstractCited forIDENTIFICATION IN THE TFIIH BASAL TRANSCRIPTION FACTOR, FUNCTION, CATALYTIC ACTIVITYCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 273:34444-34453 (1998)Cited in20
Regulation of CAK kinase activity by p53.Schneider E., Montenarh M., Wagner P.View abstractCited forFUNCTION AS CDK2 KINASE, IDENTIFICATION IN COMPLEX WITH TP53, ACTIVITY REGULATIONCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCOncogene 17:2733-2741 (1998)Cited in2
Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7.Tirode F., Busso D., Coin F., Egly J.-M.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 3:87-95 (1999)Cited in10Mapped to37
Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 histidine triad proteins.Korsisaari N., Makela T.P.View abstractCited forINTERACTION WITH HINTI, MUTAGENESIS OF LYS-41 AND THR-170, SUBCELLULAR LOCATIONCategoriesDisease & Variants, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 275:34837-34840 (2000)Cited in4
The FBP interacting repressor targets TFIIH to inhibit activated transcription.Liu J., He L., Collins I., Ge H., Libutti D., Li J., Egly J.-M., Levens D.View abstractCited forINTERACTION WITH PUF60CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 5:331-341 (2000)Cited in5
Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.Garrett S., Barton W.A., Knights R., Jin P., Morgan D.O., Fisher R.P.View abstractCited forPHOSPHORYLATION AT SER-164 AND THR-170 BY CDK2, FUNCTION AS CDK2 KINASECategoriesPTM / Processing, FunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 21:88-99 (2001)Cited in2
Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells.Bicaku E., Patel R., Acevedo-Duncan M.View abstractCited forINTERACTION WITH PRKCI, SUBCELLULAR LOCATIONCategoriesInteraction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCTissue Cell 37:53-58 (2005)Cited in2Mapped to9
Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.Larochelle S., Batliner J., Gamble M.J., Barboza N.M., Kraybill B.C., Blethrow J.D., Shokat K.M., Fisher R.P.View abstractCited forFUNCTION AS SPT5/SUPT5H AND CDK KINASE, MUTAGENESIS OF PHE-91, IDENTIFICATION IN CAK COMPLEXCategoriesFunction, Disease & Variants, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Mol. Biol. 13:55-62 (2006)Cited in3Mapped to4
Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.Larochelle S., Merrick K.A., Terret M.-E., Wohlbold L., Barboza N.M., Zhang C., Shokat K.M., Jallepalli P.V., Fisher R.P.View abstractCited forFUNCTION IN CELL CYCLE REGULATIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 25:839-850 (2007)Cited in1Mapped to15
Recognition of Cdk2 by Cdk7.Lolli G., Johnson L.N.View abstractCited forFUNCTION AS CDK2 KINASE, INTERACTION WITH CDK2CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProteins 67:1048-1059 (2007)Cited in2
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. IIIView abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Proteome Res. 7:1346-1351 (2008)Cited in99+99+
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-7; SER-164 AND SER-321, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 31:438-448 (2008)Cited in99+99+
Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7.Lewis A.E., Rusten M., Hoivik E.A., Vikse E.L., Hansson M.L., Wallberg A.E., Bakke M.View abstractCited forFUNCTION AS SF1/NR5A1 KINASE, INTERACTION WITH SF1/NR5A1CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Endocrinol. 22:91-104 (2008)Cited in2Mapped to10
A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-164 AND THR-170, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 105:10762-10767 (2008)Cited in99+99+
TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II.Akhtar M.S., Heidemann M., Tietjen J.R., Zhang D.W., Chapman R.D., Eick D., Ansari A.Z.View abstractCited forFUNCTION AS POLR2A CTD KINASECategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 34:387-393 (2009)Cited in2Mapped to10