P50110 · SAM37_YEAST

Function

function

Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex.

Miscellaneous

Present with 1580 molecules/cell in log phase SD medium.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentmitochondrial outer membrane
Cellular Componentmitochondrion
Cellular ComponentSAM complex
Biological Processmitochondrial outer membrane translocase complex assembly
Biological Processmitochondrion organization
Biological Processphospholipid transport
Biological Processprotein import into mitochondrial matrix
Biological Processprotein insertion into mitochondrial outer membrane

Keywords

Enzyme and pathway databases

Protein family/group databases

    • 1.B.33.3.1the outer membrane protein insertion porin (bam complex) (ompip) family

Names & Taxonomy

Protein names

  • Recommended name
    Sorting assembly machinery 37 kDa subunit
  • Alternative names
    • MAS37 protein
    • Mitochondrial 37 kDa outer membrane protein

Gene names

    • Name
      SAM37
    • Synonyms
      MAS37, PET3027, TOM37
    • ORF names
      YM9796.13C
    • Ordered locus names
      YMR060C

Organism names

Accessions

  • Primary accession
    P50110
  • Secondary accessions
    • D6VZN4

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane17-33Helical
Transmembrane247-265Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000726301-327Sorting assembly machinery 37 kDa subunit

Proteomic databases

PTM databases

Interaction

Subunit

Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which at least consists of SAM35, SAM37 and SAM50. SAM37 interacts with TOM70.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P50110SAM35 P146938EBI-2347180, EBI-24602
BINARY P50110SAM50 P539695EBI-2347180, EBI-28646

Complex viewer

View interactors in UniProtKB
View CPX-1744 in Complex Portal

Protein-protein interaction databases

Miscellaneous

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    37,493
  • Last updated
    1996-10-01 v1
  • Checksum
    D4ABA929CE5CAD16
MVKGSVHLWGKDGKASLISVDSIALVWFIKLCTSEEAKSMVAGLQIVFSNNTDLSSDGKLPVLILDNGTKVSGYVNIVQFLHKNICTSKYEKGTDYEEDLAIVRKKDRLLEYSLLNYVDVEISRLTDYQLFLNTKNYNEYTKKLFSKLLYFPMWYNTPLQLRSQARENCEEIIGSLTLEDDEEFVESKAMESASQLAQSKTFKIAHKNKIKGKQELQQVKYNLQFDNRLQSCVSNWLAARKKLDDSVILSSDLLFLANLYVQLGLPDGNRIRSKLEQTFGSELLNSMSNKIDDFVHRPSNNLEQRDPQFREQGNVVMSLYNLACKYI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X62565
EMBL· GenBank· DDBJ
CAA44438.1
EMBL· GenBank· DDBJ
Genomic DNA
Z49703
EMBL· GenBank· DDBJ
CAA89770.1
EMBL· GenBank· DDBJ
Genomic DNA
AY557989
EMBL· GenBank· DDBJ
AAS56315.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006946
EMBL· GenBank· DDBJ
DAA09958.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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