Molecular cloning of a novel human cdc2/CDC28-like protein kinase.Johnson K.W., Smith K.A.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 266:3402-3407 (1991)Cited in1
Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases.Hanes J.J., der Kammer H., Klaudiny J.J., Scheit K.H.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Mol. Biol. 244:665-672 (1994)Cited in4Mapped to1
Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)TissueAmygdalaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 36:40-45 (2004)Cited in99+99+
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K.[...], Wilson R.K.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 434:724-731 (2005)Cited in99+99+
No title available.Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H.[...], Venter J.C.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUL-2005)Cited in99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)TissueBlood, BoneCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
The CLK family kinases, CLK1 and CLK2, phosphorylate and activate the tyrosine phosphatase, PTP-1B.Moeslein F.M., Myers M.P., Landreth G.E.View abstractCited forFUNCTION, CATALYTIC ACTIVITYCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 274:26697-26704 (1999)Cited in4
Beacon interacts with cdc2/cdc28-like kinases.Kantham L., Kerr-Bayles L., Godde N., Quick M., Webb R., Sunderland T., Bond J., Walder K., Augert G., Collier G.View abstractCited forINTERACTION WITH UBL5CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 304:125-129 (2003)Cited in4
An unappreciated role for RNA surveillance.Hillman R.T., Green R.E., Brenner S.E.View abstractCited forSPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Biol. 5:R8.1-R8.16 (2004)Cited in96
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 127:635-648 (2006)Cited in99+99+Mapped to1
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-61 AND SER-140, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 31:438-448 (2008)Cited in99+99+
A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-138 AND SER-140, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 105:10762-10767 (2008)Cited in99+99+
Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.Eisenreich A., Bogdanov V.Y., Zakrzewicz A., Pries A., Antoniak S., Poller W., Schultheiss H.P., Rauch U.View abstractCited forFUNCTION, ALTERNATIVE SPLICING, TISSUE SPECIFICITYCategoriesFunction, Sequences, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCirc. Res. 104:589-599 (2009)Cited in6Mapped to10
Large-scale proteomics analysis of the human kinome.Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Proteomics 8:1751-1764 (2009)Cited in99+99+
Toward a comprehensive characterization of a human cancer cell phosphoproteome.Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinoma, ErythroleukemiaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Proteome Res. 12:260-271 (2013)Cited in99+99+
Patterns of somatic mutation in human cancer genomes.Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A.[...], Stratton M.R.View abstractCited forVARIANTS [LARGE SCALE ANALYSIS] PHE-61; GLY-118; SER-307 AND THR-440CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 446:153-158 (2007)Cited in99+
Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate.Lindberg M.F., Deau E., Miege F., Greverie M., Roche D., George N., George P., Merlet L., Gavard J.[...], Meijer L.View abstractCategoriesStructureSourcePDB: 8P08PubMedEurope PMCJ Med Chem 66:15648-15670 (2023)Mapped to1
Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B.Deau E., Lindberg M.F., Miege F., Roche D., George N., George P., Kramer A., Knapp S., Meijer L.View abstractCategoriesStructureSourcePDB: 8P04PubMedEurope PMCJ Med Chem 66:10694-10714 (2023)Mapped to2
Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3.Schroder M., Filippakopoulos P., Schwalm M.P., Ferrer C.A., Drewry D.H., Knapp S., Chaikuad A.View abstractCategoriesStructureSourcePDB: 7AK3PubMedEurope PMCInt J Mol Sci 21:E7953-E7953 (2020)Mapped to2
Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.Dekel N., Eisenberg-Domovich Y., Karlas A., Meyer T.F., Bracher F., Lebendiker M., Danieli T., Livnah O.View abstractCategoriesStructureSourcePDB: 6QTYPubMedEurope PMCProtein Expr Purif 176:105742-105742 (2020)Mapped to1
DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity.Schroder M., Bullock A.N., Fedorov O., Bracher F., Chaikuad A., Knapp S.View abstractCategoriesStructureSourcePDB: 6YTA, PDB: 6YTD, PDB: 6YTE, PDB: 6YTG, PDB: 6YTI, PDB: 6ZLNPubMedEurope PMCJ Med Chem 63:10224-10234 (2020)Mapped to2
A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression.Haltenhof T., Kotte A., De Bortoli F., Schiefer S., Meinke S., Emmerichs A.K., Petermann K.K., Timmermann B., Imhof P.[...], Heyd F.View abstractCategoriesStructureSourcePDB: 6TW2PubMedEurope PMCMol Cell 78:57-69.e4 (2020)Mapped to1
Structural Basis for the Selective Inhibition of Cdc2-Like Kinases by CX- 4945.Lee J.Y., Yun J.S., Kim W.K., Chun H.S., Jin H., Cho S., Chang J.H.View abstractCategoriesStructureSourcePDB: 6KHDPubMedEurope PMCBiomed Res Int 2019:6125068-6125068 (2019)Mapped to3
New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.Tazarki H., Zeinyeh W., Esvan Y.J., Knapp S., Chatterjee D., Schroder M., Joerger A.C., Khiari J., Josselin B.[...], Moreau P.View abstractCategoriesStructureSourcePDB: 6Q8K, PDB: 6Q8PPubMedEurope PMCEur J Med Chem 166:304-317 (2019)Mapped to1
Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.Nemec V., Hylsova M., Maier L., Flegel J., Sievers S., Ziegler S., Schroder M., Berger B.T., Chaikuad A.[...], Paruch K.View abstractCategoriesStructureSourcePDB: 6I5H, PDB: 6I5I, PDB: 6I5K, PDB: 6I5LPubMedEurope PMCAngew Chem Int Ed Engl 58:1062-1066 (2019)Mapped to1