Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

P49583 · PCY1_CAEEL

  • Protein
    Putative choline-phosphate cytidylyltransferase
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Pathway

Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.

Features

Showing features for binding site.

136250100150200250300350
TypeIDPosition(s)Description
Binding site88-96CTP (UniProtKB | ChEBI)
Binding site126CTP (UniProtKB | ChEBI)
Binding site126substrate
Binding site155substrate
Binding site172-173CTP (UniProtKB | ChEBI)
Binding site177CTP (UniProtKB | ChEBI)
Binding site200-204CTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functioncholine-phosphate cytidylyltransferase activity
Molecular Functionphosphatidylcholine binding
Biological Processphosphatidylcholine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative choline-phosphate cytidylyltransferase
  • EC number
  • Alternative names
    • CTP:phosphocholine cytidylyltransferase (CCT; CT)
    • Phosphorylcholine transferase

Gene names

    • ORF names
      F08C6.2

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    P49583

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002084581-362Putative choline-phosphate cytidylyltransferase

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region1-25Disordered
Region296-362Disordered
Compositional bias333-362Basic and acidic residues

Sequence similarities

Belongs to the cytidylyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    362
  • Mass (Da)
    41,769
  • Last updated
    2003-06-20 v2
  • MD5 Checksum
    3387D7BA48B5A6C3731EA9C3D427CD2F
MFIHKQEKMPQRKRTMDSPQEEDVEVKKKATEVEYVVRSLASDEPAPFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIRDYDKYVRRNLQRGYSPKELNVGFLAASKYQIQNKVDSLKSKGIELLSTWKSKSDDIIRDFIDTFHKDGGLNAFGGRLKGIMSMSRSPSPSPHEGSPTGIEHHLETQDEEEEEEALEEEKVVEQKIVEKKEVVKKRSSRNKAKTPLEY

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
Q3HKC4Q3HKC4_CAEELpcyt-1354

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias333-362Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FO080866
EMBL· GenBank· DDBJ
CCD67344.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help