P48813 · GNP1_YEAST

Function

function

High affinity transport of glutamine. Also transports Leu, Ser, Thr, Cys, Met and Asn.

Miscellaneous

Present with 10600 molecules/cell in log phase SD medium.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell periphery
Cellular Componentcellular bud neck
Cellular Componentendoplasmic reticulum
Cellular Componentmembrane
Cellular Componentmitochondrial membrane
Cellular Componentmitochondrion
Molecular Functionamino acid transmembrane transporter activity
Molecular FunctionL-proline transmembrane transporter activity
Biological Processamino acid transmembrane transport
Biological Processamino acid transport
Biological Processintracellular sphingolipid homeostasis
Biological Processserine import across plasma membrane
Biological Processtransmembrane transport

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    High-affinity glutamine permease

Gene names

    • Name
      GNP1
    • ORF names
      D9719.14
    • Ordered locus names
      YDR508C

Organism names

Accessions

  • Primary accession
    P48813
  • Secondary accessions
    • D6VTD0

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-154Cytoplasmic
Transmembrane155-175Helical
Topological domain176-177Mitochondrial intermembrane
Transmembrane178-198Helical
Topological domain199-219Cytoplasmic
Transmembrane220-240Helical
Topological domain241-264Mitochondrial intermembrane
Transmembrane265-285Helical
Topological domain286-289Cytoplasmic
Transmembrane290-310Helical
Topological domain311-342Mitochondrial intermembrane
Transmembrane343-363Helical
Topological domain364-381Cytoplasmic
Transmembrane382-402Helical
Topological domain403-432Mitochondrial intermembrane
Transmembrane433-453Helical
Topological domain454-481Cytoplasmic
Transmembrane482-502Helical
Topological domain503-506Mitochondrial intermembrane
Transmembrane507-527Helical
Topological domain528-560Cytoplasmic
Transmembrane561-581Helical
Topological domain582-590Mitochondrial intermembrane
Transmembrane591-611Helical
Topological domain612-663Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, modified residue, cross-link.

TypeIDPosition(s)Description
ChainPRO_00000541521-663High-affinity glutamine permease
Modified residue29Phosphoserine
Cross-link34Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Cross-link39Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Cross-link41Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Cross-link61Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Modified residue113Phosphoserine
Modified residue124Phosphoserine
Modified residue127Phosphothreonine
Cross-link132Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)

Keywords

Proteomic databases

PTM databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P48813SHR3 Q027743EBI-7758, EBI-17099

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-24Disordered
Region87-117Disordered
Compositional bias90-117Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    663
  • Mass (Da)
    73,598
  • Last updated
    1996-10-01 v2
  • Checksum
    9A5ED9CF7C1DD977
MTLGNRRHGRNNEGSSNMNMNRNDLDDVSHYEMKEIQPKEKQIGSIEPENEVEYFEKTVEKTIENMEYEGEHHASYLRRFIDSFRRAEGSHANSPDSSNSNGTTPISTKDSSSQLDNELNRKSSYITVDGIKQSPQEQEQKQENLKKSIKPRHTVMMSLGTGIGTGLLVGNSKVLNNAGPGGLIIGYAIMGSCVYCIIQACGELAVIYSDLIGGFNTYPLFLVDPALGFSVAWLFCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVVIFYVLIVVINVFGAKGYAEADFFFNCCKILMIVGFFILAIIIDCGGAGTDGYIGSKYWRDPGAFRGDTPIQRFKGVVATFVTAAFAFGMSEQLAMTASEQSNPRKAIPSAAKKMIYRILFVFLASLTLVGFLVPYTSDQLLGAAGSATKASPYVIAVSSHGVRVVPHFINAVILLSVLSVANGAFYTSSRILMSLAKQGNAPKCFDYIDREGRPAAAMLVSALFGVIAFCASSKKEEDVFTWLLAISGLSQLFTWITICLSHIRFRRAMKVQGRSLGEVGYKSQVGVWGSAYAVLMMVLALIAQFWVAIAPIGGGGKLSAQSFFENYLAMPIWIALYIFYKVWKKDWSLFIPADKVDLVSHRNIFDEELLKQEDEEYKERLRNGPYWKRVLDFWC

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias90-117Polar residues
Sequence conflict319in Ref. 1; AAB48002

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U21643
EMBL· GenBank· DDBJ
AAB48002.1
EMBL· GenBank· DDBJ
Genomic DNA
U33057
EMBL· GenBank· DDBJ
AAB64950.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006938
EMBL· GenBank· DDBJ
DAA12340.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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