P48642 · GSHRC_ORYSJ

Function

function

Maintains high levels of reduced glutathione in the cytosol.

Miscellaneous

The active site is a redox-active disulfide bond.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site61-70FAD (UniProtKB | ChEBI)
Binding site231NADP+ (UniProtKB | ChEBI)
Binding site237NADP+ (UniProtKB | ChEBI)
Active site469Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionglutathione-disulfide reductase (NADPH) activity
Molecular FunctionNADP binding
Molecular Functionthioredoxin-disulfide reductase (NADPH) activity
Biological Processcell redox homeostasis
Biological Processglutathione metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione reductase, cytosolic
  • EC number
  • Short names
    GR; GRase

Gene names

    • Name
      GRC2
    • Synonyms
      RGRC2
    • ORF names
      OJ1293_E04.4-1, OsJ_08842
      , OSJNBa0053L11.26-1
    • Ordered locus names
      Os02g0813500
      , LOC_Os02g56850

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    P48642
  • Secondary accessions
    • A0A0P0VR51
    • Q0DWI9
    • Q6K3E8
    • Q8GRV3
    • Q9ZNS8

Proteomes

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, disulfide bond, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00000679631-496UniProtGlutathione reductase, cytosolic
Disulfide bond70↔75UniProtRedox-active
Modified residue (large scale data)86PTMeXchangePhosphoserine
Modified residue (large scale data)487PTMeXchangePhosphoserine

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    496
  • Mass (Da)
    53,507
  • Last updated
    2001-09-26 v2
  • Checksum
    A27FEE5D847F97F6
MARKMLKDEEVEVAVTDGGSYDYDLFVIGAGSGGVRGSRTSASFGAKVAICELPFHPISSDWQGGHGGTCVIRGCVPKKILVYGSSFRGEFEDAKNFGWEINGDINFNWKRLLENKTQEIVRLNGVYQRILGNSGVTMIEGAGSLVDAHTVEVTKPDGSKQRYTAKHILIATGSRAQRVNIPGKELAITSDEALSLEELPKRAVILGGGYIAVEFASIWKGMGAHVDLFYRKELPLRGFDDEMRTVVASNLEGRGIRLHPGTNLSELSKTADGIKVVTDKGEEIIADVVLFATGRTPNSQRLNLEAAGVEVDNIGAIKVDDYSRTSVPNIWAVGDVTNRINLTPVALMEATCFSKTVFGGQPTKPDYRDVPCAVFSIPPLSVVGLSEQQALEEAKSDVLVYTSSFNPMKNSISKRQEKTVMKLVVDSETDKVLGASMCGPDAPEIIQGMAVALKCGATKATFDSTVGIHPSAAEEFVTMRTLTRRVSPSSKPKTNL

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0P0VR27A0A0P0VR27_ORYSJOs02g0813500190
A0A0P0VR44A0A0P0VR44_ORYSJOs02g0813500159

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict31in Ref. 1; BAA11214
Sequence conflict48in Ref. 1; BAA11214
Sequence conflict97in Ref. 1; BAA11214

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D78136
EMBL· GenBank· DDBJ
BAA11214.1
EMBL· GenBank· DDBJ
mRNA
D85751
EMBL· GenBank· DDBJ
BAA36283.1
EMBL· GenBank· DDBJ
mRNA
AB009592
EMBL· GenBank· DDBJ
BAA37092.1
EMBL· GenBank· DDBJ
Genomic DNA
AP004120
EMBL· GenBank· DDBJ
BAD21653.1
EMBL· GenBank· DDBJ
Genomic DNA
AP005691
EMBL· GenBank· DDBJ
BAD22392.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008208
EMBL· GenBank· DDBJ
BAF10399.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014958
EMBL· GenBank· DDBJ
BAS81540.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000139
EMBL· GenBank· DDBJ
EAZ25050.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136760
EMBL· GenBank· DDBJ
AAN15933.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136761
EMBL· GenBank· DDBJ
AAN15934.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136762
EMBL· GenBank· DDBJ
AAN15935.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136763
EMBL· GenBank· DDBJ
AAN15936.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136764
EMBL· GenBank· DDBJ
AAN15937.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136765
EMBL· GenBank· DDBJ
AAN15938.1
EMBL· GenBank· DDBJ
Genomic DNA
AY136766
EMBL· GenBank· DDBJ
AAN15939.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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