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P48537 · CRTI_CERNC

Function

function

Phytoene desaturase involved in the carotenoid biosynthesis pathway. Converts phytoene into 3,4-didehydrolycopene via the intermediary of phytofluene, zeta-carotene, neurosporene and lycopene, by introducing up to five double bonds into phytoene (By similarity).

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Pathway

Carotenoid biosynthesis; lycopene biosynthesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionoxidoreductase activity, acting on the CH-CH group of donors
Biological Processcarotenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phytoene desaturase
  • EC number
  • Alternative names
    • Phytoene desaturase (3,4-didehydrolycopene-forming)

Gene names

    • Name
      PDH1

Organism names

Accessions

  • Primary accession
    P48537

Subcellular Location

Membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane598-618Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_000006769424-621Phytoene desaturase

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region394-425Disordered
Compositional bias399-420Polar residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    621
  • Mass (Da)
    69,530
  • Last updated
    1996-02-01 v1
  • MD5 Checksum
    5ECB836DFDBDFD1D1475FC642342FA27
MPSTSKRPTAIVIGSGVGGVSTAARLARAGFHVTVLEKNNFTGGRCSLIHHEGYRFDQGPSLLLLPGLFHRTFAELGTSLEQEGVKLLKCEPNYMIHFSDGEKFTLSSDLSVMKTEVEKWEGKEGYTRYLEFLKESHGHYELSVREVLLRNFEGLTAMLRPEFLRHLLQLHPFESIWTRAGKYFWTERLRRVFTFGSMYMGMSPFDAPGTYSLLQYTELAEGIWYPVGGFHRVVEALVKIGEREGVDFRMETAVKKILLSEDGGVAKGVELEDGRRLEADVVVNNSDLVYAYEKLLPIKTPYAESLKGRPGSCSSISFYWALDRQVPELEAHNIFLADEYRESFDSIFKKHLIPDEPSFYVNVPSRVDSTAAPEGKDSVVVLVPVGHLLEEDRHASQAHQLSASRNGHISSASPPDQPGLTPTEKQDWPAMISLARKTILSTIQSRTNVDLTPLIIHESTNSPLSWKQTFNLDRGAILGLSHSFFNVLCFRPTTRARKPGAFDAQLLKFGVLGRAAEVIIDAFRGRGKDIKGLYMVGASAHPGTGVPICLAGGALVAEQICGDYGVDIPWKEEERKGRDVGGKRKLDVLESPMWLDSWEQWVSVLIYLLVGIFAWLWMKFR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias399-420Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U03903
EMBL· GenBank· DDBJ
AAB86988.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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