P48534 · APX1_PEA

Function

function

Plays a key role in hydrogen peroxide removal.

Miscellaneous

Binds one cation per subunit; probably K+, but might also be Ca2+.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.

Features

Showing features for site, active site, binding site.

125020406080100120140160180200220240
TypeIDPosition(s)Description
Site38Transition state stabilizer
Active site42Proton acceptor
Binding site163Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue
Binding site164K+ (UniProtKB | ChEBI)
Binding site180K+ (UniProtKB | ChEBI)
Binding site182K+ (UniProtKB | ChEBI)
Binding site185K+ (UniProtKB | ChEBI)
Binding site187K+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast
Molecular Functionheme binding
Molecular FunctionL-ascorbate peroxidase activity
Molecular Functionmetal ion binding
Biological Processcellular response to oxidative stress
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to reactive oxygen species

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    L-ascorbate peroxidase, cytosolic
  • EC number
  • Short names
    AP
  • Alternative names
    • PsAPx01

Gene names

    • Name
      APX1
    • Synonyms
      APPX1

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Little Marvel
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > Hologalegina > IRL clade > Fabeae > Pisum

Accessions

  • Primary accession
    P48534

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00000555972-250L-ascorbate peroxidase, cytosolic

Expression

Induction

By stress.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region113-137Disordered
Compositional bias115-137Basic and acidic residues

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    250
  • Mass (Da)
    27,193
  • Last updated
    2007-01-23 v2
  • Checksum
    6F51006D0A13B42C
MGKSYPTVSPDYQKAIEKAKRKLRGFIAEKKCAPLILRLAWHSAGTFDSKTKTGGPFGTIKHQAELAHGANNGLDIAVRLLEPIKEQFPIVSYADFYQLAGVVAVEITGGPEVPFHPGREDKPEPPPEGRLPDATKGSDHLRDVFGKAMGLSDQDIVALSGGHTIGAAHKERSGFEGPWTSNPLIFDNSYFTELLTGEKDGLLQLPSDKALLTDSVFRPLVEKYAADEDVFFADYAEAHLKLSELGFAEA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias115-137Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M93051
EMBL· GenBank· DDBJ
AAA33645.1
EMBL· GenBank· DDBJ
Genomic DNA
X62077
EMBL· GenBank· DDBJ
CAA43992.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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