P48445 · BPL1_YEAST

Function

function

Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase.

Miscellaneous

Present with 1970 molecules/cell in log phase SD medium.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionbiotin-[acetyl-CoA-carboxylase] ligase activity
Molecular Functionbiotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
Molecular Functionbiotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
Molecular Functionbiotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity
Molecular Functionbiotin-[pyruvate-carboxylase] ligase activity
Biological Processprotein modification process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biotin--protein ligase
  • EC number
  • Alternative names
    • Biotin apo-protein ligase

Including 4 domains:

  • Recommended name
    Biotin--[methylmalonyl-CoA-carboxytransferase] ligase
  • EC number
  • Recommended name
    Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase
  • EC number
  • Alternative names
    • Holocarboxylase synthetase (HCS)
  • Recommended name
    Biotin--[methylcrotonoyl-CoA-carboxylase] ligase
  • EC number
  • Recommended name
    Biotin--[acetyl-CoA-carboxylase] ligase
  • EC number

Gene names

    • Name
      BPL1
    • Synonyms
      ACC2
    • ORF names
      D2140
    • Ordered locus names
      YDL141W

Organism names

Accessions

  • Primary accession
    P48445
  • Secondary accessions
    • D6VRK7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000649811-690Biotin--protein ligase

Proteomic databases

PTM databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain378-606BPL/LPL catalytic

Sequence similarities

Belongs to the biotin--protein ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    690
  • Mass (Da)
    76,363
  • Last updated
    1996-02-01 v1
  • Checksum
    ADA6BFE411C656AB
MNVLVYNGPGTTPGSVKHAVESLRDFLEPYYAVSTVNVKVLQTEPWMSKTSAVVFPGGADLPYVQACQPIISRLKHFVSKQGGVFIGFCAGGYFGTSRVEFAQGDPTMEVSGSRDLRFFPGTSRGPAYNGFQYNSEAGARAVKLNLPDGSQFSTYFNGGAVFVDADKFDNVEILATYAEHPDVPSSDSGKGQSENPAAVVLCTVGRGKVLLTGPHPEFNVRFMRKSTDKHFLETVVENLKAQEIMRLKFMRTVLTKTGLNCNNDFNYVRAPNLTPLFMASAPNKRNYLQEMENNLAHHGMHANNVELCSELNAETDSFQFYRGYRASYDAASSSLLHKEPDEVPKTVIFPGVDEDIPPFQYTPNFDMKEYFKYLNVQNTIGSLLLYGEVVTSTSTILNNNKSLLSSIPESTLLHVGTIQVSGRGRGGNTWINPKGVCASTAVVTMPLQSPVTNRNISVVFVQYLSMLAYCKAILSYAPGFSDIPVRIKWPNDLYALSPTYYKRKNLKLVNTGFEHTKLPLGDIEPAYLKISGLLVNTHFINNKYCLLLGCGINLTSDGPTTSLQTWIDILNEERQQLHLDLLPAIKAEKLQALYMNNLEVILKQFINYGAAEILPSYYELWLHSNQIVTLPDHGNTQAMITGITEDYGLLIAKELVSGSSTQFTGNVYNLQPDGNTFDIFKSLIAKKVQS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U27182
EMBL· GenBank· DDBJ
AAC49057.1
EMBL· GenBank· DDBJ
Genomic DNA
X96876
EMBL· GenBank· DDBJ
CAA65617.1
EMBL· GenBank· DDBJ
Genomic DNA
Z74189
EMBL· GenBank· DDBJ
CAA98714.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006938
EMBL· GenBank· DDBJ
DAA11717.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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