P48419 · C75A3_PETHY

  • Protein
    Flavonoid 3',5'-hydroxylase 2
  • Gene
    CYP75A3
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Catalyzes the 3'5'-hydroxylation of naringenin and eriodictyol to form 5,7,3,'4',5'-pentahydroxyflavanone and 3',5'-hydroxylation of dihydrokaempferol and dihydroquercetin to form dihydromyricetin.

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Pathway

Pigment biosynthesis; anthocyanin biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site443Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Molecular Functionflavonoid 3',5'-hydroxylase activity
Molecular Functionheme binding
Molecular Functioniron ion binding
Biological Processanthocyanin-containing compound biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Flavonoid 3',5'-hydroxylase 2
  • EC number
  • Short names
    F3'5'H
  • Alternative names
    • CYPLXXVA3
    • Cytochrome P450 75A3

Gene names

    • Name
      CYP75A3
    • Synonyms
      HF2

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Old Glory Blue
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Petunioideae > Petunia

Accessions

  • Primary accession
    P48419

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000521301-508Flavonoid 3',5'-hydroxylase 2

Expression

Tissue specificity

Flowers.

Structure

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    508
  • Mass (Da)
    56,721
  • Last updated
    1996-02-01 v1
  • Checksum
    70989FF2B3AD4FD8
MVLLSELAAATLIFLTTHIFISTLLSITNGRRLPPGPRGWPVIGALPLLGAMPHVSLAKMAKKYGAIMYLKVGTCGMVVASTPDAAKAFLKTLDLNFSNRPPNAGATHLAYGAQDMVFAHYGPRWKLLRKLSNLHMLGGKALENWANVRANELGHMLKSMFDMSREGERVVVAEMLTFAMANMIGQVILSKRVFVNKGVEVNEFKDMVVELMTTAGYFNIGDFIPCLAWMDLQGIEKGMKRLHKKFDALLTKMFDEHKATSYERKGKPDFLDCVMENRDNSEGERLSTTNIKALLLNLFTAGTDTSSSAIEWALAEMMKNPAILKKAQGEMDQVIGNNRRLLESDIPNLPYLRAICKETFRKHPSTPLNLPRISNEPCIVDGYYIPKNTRLSVNIWAIGRDPEVWENPLEFYPERFLSGRNSKIDPRGNDFELIPFGAGRRICAGTRMGIVMVEYILGTLVHSFDWKLPSEVIELNMEEAFGLALQKAVPLEAMVTPRLPIDVYAPLA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z22544
EMBL· GenBank· DDBJ
CAA80265.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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