P48269 · CCSA_CHLRE

Function

function

Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.

Miscellaneous

Met-1 is the initiator; however when Met-1 is mutated a low amount of protein may be produced, probably from Met-20.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast thylakoid membrane
Molecular Functionheme binding
Biological Processcytochrome complex assembly

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome c biogenesis protein CcsA

Gene names

    • Name
      ccsA

Encoded on

  • Chloroplast

Organism names

Accessions

  • Primary accession
    P48269
  • Secondary accessions
    • B7U1H0

Proteomes

Subcellular Location

Features

Showing features for transmembrane, topological domain.

TypeIDPosition(s)Description
Transmembrane15-32Helical
Topological domain33-208Lumenal
Transmembrane209-233Helical
Topological domain234-260Stromal
Transmembrane261-278Helical
Topological domain279-295Lumenal
Transmembrane296-313Helical
Topological domain314-323Stromal
Transmembrane324-342Helical
Topological domain343-353Lumenal

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis1Almost no c-type holocytochrome formation.
Mutagenesis20No effect on c-type holocytochrome formation.
Mutagenesis212Abrogates production of c-type holocytochrome.
Mutagenesis279Abrogates production of c-type holocytochrome.
Mutagenesis284Severely reduces amounts of c-type holocytochrome produced.
Mutagenesis288Reduced amounts of c-type holocytochromes produced.
Mutagenesis288-290Reduced amounts of c-type holocytochromes produced; a more severe reduction than seen with either single mutation.
Mutagenesis290Reduced amounts of c-type holocytochromes produced.
Mutagenesis291Abrogates production of c-type holocytochrome. No assembly of cytochrome c6 occurs.
Mutagenesis291Abrogates production of c-type holocytochrome. Permits small amounts of cytochrome c6 assembly.
Mutagenesis296No effect on activity.
Mutagenesis301No effect on activity.
Mutagenesis309Abrogates production of c-type holocytochrome.
Mutagenesis347Abrogates production of c-type holocytochrome.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002016001-353Cytochrome c biogenesis protein CcsA

Proteomic databases

Interaction

Subunit

May interact with Ccs1.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    353
  • Mass (Da)
    39,983
  • Last updated
    2003-07-11 v2
  • Checksum
    3D46ABDF51044C4B
MNFVNLEQIENSLRNATFCMLFLTTFLYWFYTAFYSTNPQQIINPLSLTNIKTNFTYPDGFQANNINVSTTYLPINPVLNTEREEQPEANGTNGLLGVSSLVVNLKSIAIPRIMMGVSNLLLVLLLLVRWEKSGHFPLSNLYESLMFLAWCCTFLYLLYCTSFTLLVEKMLGSLIAPCSLLMNAFATFSLPKEMQQASPLVPALQSNWLMMHVTVMIISYATLIIGSLLSILFLILFKHKKGTPKKYDNFINNLDALSYRIIGLGFPFLTIGILSGAVWANEAWGSYWSWDPKETWALLTWLVFAIYLHTRLTKGWEGEKPAIIAAVGFLVVWFCYLGVNLIGEGLHSYGFFN

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict342in Ref. 1; AAA76600

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U15556
EMBL· GenBank· DDBJ
AAA76600.1
EMBL· GenBank· DDBJ
Genomic DNA
U09190
EMBL· GenBank· DDBJ
AAB03815.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ423446
EMBL· GenBank· DDBJ
ACJ50117.1
EMBL· GenBank· DDBJ
Genomic DNA
BK000554
EMBL· GenBank· DDBJ
DAA00929.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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