P48007 · PIST_ARATH
- ProteinFloral homeotic protein PISTILLATA
- GenePI
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids208 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Probable transcription factor involved in the genetic control of flower development. Is required for normal development of petals and stamens in the wild-type flower. Forms a heterodimer with APETALA3 that is required for autoregulation of both AP3 and PI genes. AP3/PI heterodimer interacts with APETALA1 or SEPALLATA3 to form a ternary complex that could be responsible for the regulation of the genes involved in the flower development. AP3/PI heterodimer activates the expression of NAP. AP3/PI prevents GATA22/GNL and GATA21/GNC expression (PubMed:18417639).
Miscellaneous
Mutations in PI cause transformation of petals into sepals and stamina into carpels.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | protein dimerization activity | |
Molecular Function | RNA polymerase II transcription regulatory region sequence-specific DNA binding | |
Molecular Function | transcription cis-regulatory region binding | |
Biological Process | cell differentiation | |
Biological Process | positive regulation of transcription by RNA polymerase II | |
Biological Process | specification of floral organ identity |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameFloral homeotic protein PISTILLATA
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionP48007
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | 29 | in strain: cv. Cvi-0 | ||||
Sequence: V → A | ||||||
Natural variant | 38 | in strain: cv. Co-1 | ||||
Sequence: L → P | ||||||
Natural variant | 51 | in strain: cv. Lisse | ||||
Sequence: N → D | ||||||
Natural variant | 73 | in strain: cv. Co-1 | ||||
Sequence: K → M | ||||||
Natural variant | 75 | in strain: cv. Kent | ||||
Sequence: S → P | ||||||
Natural variant | 89 | in strain: cv. Gr-3 | ||||
Sequence: N → D | ||||||
Natural variant | 112 | in strain: cv. Lisse | ||||
Sequence: D → G | ||||||
Natural variant | 125 | in strain: cv. Gr-3 | ||||
Sequence: E → G | ||||||
Natural variant | 140 | in strain: cv. Corsacalla-1 | ||||
Sequence: M → I | ||||||
Natural variant | 142 | in strain: cv. Kent | ||||
Sequence: I → V | ||||||
Natural variant | 160 | in strain: cv. Kent | ||||
Sequence: L → I | ||||||
Natural variant | 203 | in strain: cv. Cvi-0 | ||||
Sequence: M → T |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 15 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000199482 | 1-208 | Floral homeotic protein PISTILLATA | |||
Sequence: MGRGKIEIKRIENANNRVVTFSKRRNGLVKKAKEITVLCDAKVALIIFASNGKMIDYCCPSMDLGAMLDQYQKLSGKKLWDAKHENLSNEIDRIKKENDSLQLELRHLKGEDIQSLNLKNLMAVEHAIEHGLDKVRDHQMEILISKRRNEKMMAEEQRQLTFQLQQQEMAIASNARGMMMRDHDGQFGYRVQPIQPNLQEKIMSLVID |
Proteomic databases
Expression
Induction
Positively regulated by the meristem identity proteins APETALA1 and LEAFY with the cooperation of UFO. Repressed by silencing mediated by polycomb group (PcG) protein complex containing EMF1 and EMF2.
Gene expression databases
Interaction
Subunit
Forms a heterodimer with APETALA3, capable of binding to CArG-box sequences. AP3/PI heterodimer binds AP1 or SEP3 to form a ternary complex.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | P48007 | SEP3 O22456 | 3 | EBI-1395334, EBI-592020 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-57 | MADS-box | ||||
Sequence: RGKIEIKRIENANNRVVTFSKRRNGLVKKAKEITVLCDAKVALIIFASNGKMIDY | ||||||
Coiled coil | 75-117 | |||||
Sequence: SGKKLWDAKHENLSNEIDRIKKENDSLQLELRHLKGEDIQSLN | ||||||
Domain | 84-170 | K-box | ||||
Sequence: HENLSNEIDRIKKENDSLQLELRHLKGEDIQSLNLKNLMAVEHAIEHGLDKVRDHQMEILISKRRNEKMMAEEQRQLTFQLQQQEMA |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length208
- Mass (Da)24,047
- Last updated1996-02-01 v1
- Checksum49728735AC883CCA
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8BAQ7 | A0A1P8BAQ7_ARATH | PI | 150 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
D30807 EMBL· GenBank· DDBJ | BAA06465.1 EMBL· GenBank· DDBJ | mRNA | ||
AB035137 EMBL· GenBank· DDBJ | BAA87000.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115815 EMBL· GenBank· DDBJ | AAD51984.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115816 EMBL· GenBank· DDBJ | AAD51985.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115817 EMBL· GenBank· DDBJ | AAD51986.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115818 EMBL· GenBank· DDBJ | AAD51987.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115819 EMBL· GenBank· DDBJ | AAD51988.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115820 EMBL· GenBank· DDBJ | AAD51989.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115821 EMBL· GenBank· DDBJ | AAD51990.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115822 EMBL· GenBank· DDBJ | AAD51991.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115823 EMBL· GenBank· DDBJ | AAD51992.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115824 EMBL· GenBank· DDBJ | AAD51993.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115825 EMBL· GenBank· DDBJ | AAD51994.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115826 EMBL· GenBank· DDBJ | AAD51995.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115827 EMBL· GenBank· DDBJ | AAD51996.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115828 EMBL· GenBank· DDBJ | AAD51997.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115829 EMBL· GenBank· DDBJ | AAD51998.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF115830 EMBL· GenBank· DDBJ | AAD51999.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF296825 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CP002688 EMBL· GenBank· DDBJ | AED92817.1 EMBL· GenBank· DDBJ | Genomic DNA |