P47893 · OR3A2_HUMAN
- ProteinOlfactory receptor 3A2
- GeneOR3A2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids321 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Odorant receptor.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | G protein-coupled receptor activity | |
Molecular Function | olfactory receptor activity | |
Molecular Function | signaling receptor activity | |
Biological Process | sensory perception of chemical stimulus | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOlfactory receptor 3A2
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionP47893
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-35 | Extracellular | ||||
Sequence: MSLQKLMEPEAGTNRTAVAEFILLGLVQTEEMQPV | ||||||
Transmembrane | 36-58 | Helical; Name=1 | ||||
Sequence: VFVLLLFAYLVTTGGNLSILAAV | ||||||
Topological domain | 59-66 | Cytoplasmic | ||||
Sequence: LVEPKLHA | ||||||
Transmembrane | 67-88 | Helical; Name=2 | ||||
Sequence: PMYFFLGNLSVLDVGCITVTVP | ||||||
Topological domain | 89-109 | Extracellular | ||||
Sequence: AMLGRLLSHKSTISYDACLSQ | ||||||
Transmembrane | 110-129 | Helical; Name=3 | ||||
Sequence: LFFFHLLAGMDCFLLTAMAY | ||||||
Topological domain | 130-149 | Cytoplasmic | ||||
Sequence: DRLLAICQPLTYSTRMSQTV | ||||||
Transmembrane | 150-167 | Helical; Name=4 | ||||
Sequence: QRMLVAASLACAFTNALT | ||||||
Topological domain | 168-205 | Extracellular | ||||
Sequence: HTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNE | ||||||
Transmembrane | 206-229 | Helical; Name=5 | ||||
Sequence: LLLFAVGFIMAGTPLVLIITAYSH | ||||||
Topological domain | 230-246 | Cytoplasmic | ||||
Sequence: VAAAVLRIRSVEGRKKA | ||||||
Transmembrane | 247-270 | Helical; Name=6 | ||||
Sequence: FSTCGSHLTVVCLFFGRGIFNYMR | ||||||
Topological domain | 271-281 | Extracellular | ||||
Sequence: LGSEEASDKDK | ||||||
Transmembrane | 282-301 | Helical; Name=7 | ||||
Sequence: GVGVFNTVINPMLNPLIYSL | ||||||
Topological domain | 302-321 | Cytoplasmic | ||||
Sequence: RNPDVQGALWQIFLGRRSLT |
Keywords
- Cellular component
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_062032 | 190 | in dbSNP:rs9901356 | |||
Sequence: L → V |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1 variant from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain, glycosylation, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000150518 | 1-321 | Olfactory receptor 3A2 | |||
Sequence: MSLQKLMEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPLVLIITAYSHVAAAVLRIRSVEGRKKAFSTCGSHLTVVCLFFGRGIFNYMRLGSEEASDKDKGVGVFNTVINPMLNPLIYSLRNPDVQGALWQIFLGRRSLT | ||||||
Glycosylation | 14 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 106↔198 | |||||
Sequence: CLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSC |
Keywords
- PTM
Proteomic databases
PTM databases
Structure
Sequence
- Sequence statusComplete
- Length321
- Mass (Da)35,207
- Last updated2009-04-14 v3
- Checksum642FCD0CC1660F8A
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A286YF70 | A0A286YF70_HUMAN | OR3A2 | 47 | ||
A0A286YF44 | A0A286YF44_HUMAN | OR3A2 | 30 | ||
A0A286YFF0 | A0A286YFF0_HUMAN | OR3A2 | 315 |
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 128 | in Ref. 4; AAA17448 | ||||
Sequence: A → G | ||||||
Sequence conflict | 134 | in Ref. 4; AAA17448 | ||||
Sequence: A → G | ||||||
Sequence conflict | 142 | in Ref. 4; AAA17448 | ||||
Sequence: S → R | ||||||
Sequence conflict | 171 | in Ref. 4; AAA17448 | ||||
Sequence: A → G |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC087498 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
BC095517 EMBL· GenBank· DDBJ | AAH95517.1 EMBL· GenBank· DDBJ | mRNA | ||
AF087930 EMBL· GenBank· DDBJ | AAF37318.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
U04713 EMBL· GenBank· DDBJ | AAA17448.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK004239 EMBL· GenBank· DDBJ | DAA04637.1 EMBL· GenBank· DDBJ | Genomic DNA |