ADP ribosylation factor regulates spectrin binding to the Golgi complex.Godi A., Santone I., Pertile P., Devarajan P., Stabach P.R., Morrow J.S., Di Tullio G., Polishchuk R., Petrucci T.C.[...], De Matteis M.A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCProc Natl Acad Sci U S A 95:8607-8612 (1998)Mapped to82
A role for giantin in docking COPI vesicles to Golgi membranes.Sonnichsen B., Lowe M., Levine T., Jamsa E., Dirac-Svejstrup B., Warren G.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Cell Biol 140:1013-1021 (1998)Mapped to86
Na,K-ATPase transport from endoplasmic reticulum to Golgi requires the Golgi spectrin-ankyrin G119 skeleton in Madin Darby canine kidney cells.Devarajan P., Stabach P.R., De Matteis M.A., Morrow J.S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCProc Natl Acad Sci U S A 94:10711-10716 (1997)Mapped to82
Visualization of ER-to-Golgi transport in living cells reveals a sequential mode of action for COPII and COPI.Scales S.J., Pepperkok R., Kreis T.E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCCell 90:1137-1148 (1997)Mapped to74
ER-to-Golgi transport visualized in living cells.Presley J.F., Cole N.B., Schroer T.A., Hirschberg K., Zaal K.J., Lippincott-Schwartz J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCNature 389:81-85 (1997)Mapped to84
The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner.Nakamura N., Lowe M., Levine T.P., Rabouille C., Warren G.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCCell 89:445-455 (1997)Cited in2Mapped to99+
Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles.Holleran E.A., Tokito M.K., Karki S., Holzbaur E.L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Cell Biol 135:1815-1829 (1996)Mapped to82
Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface.Wubbolts R., Fernandez-Borja M., Oomen L., Verwoerd D., Janssen H., Calafat J., Tulp A., Dusseljee S., Neefjes J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Cell Biol 135:611-622 (1996)Mapped to80
B lymphocytes secrete antigen-presenting vesicles.Raposo G., Nijman H.W., Stoorvogel W., Liejendekker R., Harding C.V., Melief C.J., Geuze H.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Exp Med 183:1161-1172 (1996)Mapped to80
Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa.Linstedt A.D., Hauri H.P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCMol Biol Cell 4:679-693 (1993)Mapped to86
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.Wang D., Ye Z., Wei W., Yu J., Huang L., Zhang H., Yue J.View abstractAnnotationCapping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.CategoriesFunction, InteractionSourceGeneRif: 830PubMedEurope PMCElife 10:e65910-e65910 (2021)Mapped to14
The contribution of TMC1 to adaptation of mechanoelectrical transduction channels in cochlear outer hair cells.Goldring A.C., Beurg M., Fettiplace R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Physiol 597:5949-5961 (2019)Mapped to56
A <i>Tmc1</i> mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells.Beurg M., Barlow A., Furness D.N., Fettiplace R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCProc Natl Acad Sci U S A 116:20743-20749 (2019)Mapped to56
Nanomechanics of tip-link cadherins.Oroz J., Galera-Prat A., Hervas R., Valbuena A., Fernandez-Bravo D., Carrion-Vazquez M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCSci Rep 9:13306-13306 (2019)Mapped to50
Ultrastructural localization of the likely mechanoelectrical transduction channel protein, transmembrane-like channel 1 (TMC1) during development of cochlear hair cells.Mahendrasingam S., Furness D.N.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCSci Rep 9:1274-1274 (2019)Mapped to51
TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.Pan B., Akyuz N., Liu X.P., Asai Y., Nist-Lund C., Kurima K., Derfler B.H., Gyoergy B., Limapichat W.[...], Holt J.R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCNeuron 99:736-753.e6 (2018)Cited in3Mapped to53
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.Ge J., Elferich J., Goehring A., Zhao H., Schuck P., Gouaux E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCElife 7:e38770-e38770 (2018)Mapped to55
Tuning Inner-Ear Tip-Link Affinity Through Alternatively Spliced Variants of Protocadherin-15.Narui Y., Sotomayor M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCBiochemistry 57:1702-1710 (2018)Mapped to53
Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice.Wang Y., Li J., Yao X., Li W., Du H., Tang M., Xiong W., Chai R., Xu Z.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCFront. Mol. Neurosci. 10:401-401 (2017)Cited in3Mapped to56
TMC2 Modifies Permeation Properties of the Mechanoelectrical Transducer Channel in Early Postnatal Mouse Cochlear Outer Hair Cells.Corns L.F., Jeng J.Y., Richardson G.P., Kros C.J., Marcotti W.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCFront Mol Neurosci 10:326-326 (2017)Mapped to51
CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival.Michel V., Booth K.T., Patni P., Cortese M., Azaiez H., Bahloul A., Kahrizi K., Labbe M., Emptoz A.[...], El-Amraoui A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCEMBO Mol. Med. 9:1711-1731 (2017)Cited in3Mapped to50
Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery.Bahloul A., Pepermans E., Raynal B., Wolff N., Cordier F., England P., Nouaille S., Baron B., El-Amraoui A.[...], Petit C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCFEBS Lett 591:2299-2310 (2017)Mapped to50
Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.Corns L.F., Johnson S.L., Kros C.J., Marcotti W.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Neurosci 36:336-349 (2016)Mapped to56
The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells.Beurg M., Goldring A.C., Fettiplace R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCJ Gen Physiol 146:233-243 (2015)Mapped to56
TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.Kurima K., Ebrahim S., Pan B., Sedlacek M., Sengupta P., Millis B.A., Cui R., Nakanishi H., Fujikawa T.[...], Kachar B.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-879448PubMedEurope PMCCell Rep 12:1606-1617 (2015)Mapped to56