P47700 · SYE_MYCGE

Function

function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

Catalytic activity

Features

Showing features for binding site.

148450100150200250300350400450
TypeIDPosition(s)Description
Binding site255ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglutamate-tRNA ligase activity
Molecular FunctiontRNA binding
Molecular Functionzinc ion binding
Biological Processglutamyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamate--tRNA ligase
  • EC number
  • Alternative names
    • Glutamyl-tRNA synthetase
      (GluRS
      )

Gene names

    • Name
      gltX
    • Ordered locus names
      MG462

Organism names

Accessions

  • Primary accession
    P47700
  • Secondary accessions
    • Q49256
    • Q49306
    • Q49490

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001196011-484Glutamate--tRNA ligase

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif10-20'HIGH' region
Motif252-256'KMSKS' region

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    484
  • Mass (Da)
    55,941
  • Last updated
    1996-02-01 v1
  • MD5 Checksum
    287285E9346703B6BCB8C682EE85265C
MEKIRTRYAPSPTGYLHVGGTRTAIFNFLLAKHFNGEFIIRIEDTDTERNIKEGINSQFDNLRWLGVIADESVYNPGNYGPYLQSQKLAVYKKLAFDLIEKNLAYRCFCSKEKLESDRKQAINNHKTPKYLGHCRNLHSKKITNHLEKNDPFTIRLKINNEAEYSWNDLVRGQITIPGSALTDIVILKANGVATYNFAVVIDDYDMEITDVLRGAEHISNTAYQLAIYQALGFKRIPRFGHLSVIVDESGKKLSKRDEKTTQFIEQFKQQGYLPEALLNFLALLGWHPQYNQEFFNLKQLIENFSLSRVVSAPAFFDIKKLQWINANYIKQLTDNAYFNFIDNYLDVKVDYLKDKNREISLLFKNQITHGVQINELIRESFATKIGVENLAKKSHILFKNIKLFLEQLAKSLQGLEEWKAEQIKTTINKVGAVFNLKGKQLFMPIRLIFTNKEHGPDLAHIIEIFDKESAINLIKQFINATNLF

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict60in Ref. 3; AAD12469
Sequence conflict230in Ref. 2
Sequence conflict362in Ref. 3

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
L43967
EMBL· GenBank· DDBJ
AAC72482.1
EMBL· GenBank· DDBJ
Genomic DNA
X61538
EMBL· GenBank· DDBJ
CAA43750.1
EMBL· GenBank· DDBJ
Genomic DNA
U02183
EMBL· GenBank· DDBJ
AAD12469.1
EMBL· GenBank· DDBJ
Genomic DNA
U02122
EMBL· GenBank· DDBJ
AAD12397.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help