P47058 · TAD2_YEAST

Function

function

Deaminates adenosine-34 to inosine in many tRNAs.

Miscellaneous

Present with 830 molecules/cell in log phase SD medium.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site, active site.

125020406080100120140160180200220240
TypeIDPosition(s)Description
Binding site54Zn2+ (UniProtKB | ChEBI); catalytic
Active site56Proton donor
Binding site88Zn2+ (UniProtKB | ChEBI); catalytic
Binding site91Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Cellular ComponenttRNA-specific adenosine-34 deaminase complex
Molecular FunctiontRNA-specific adenosine deaminase activity
Molecular FunctiontRNA-specific adenosine-34 deaminase activity
Molecular Functionzinc ion binding
Biological ProcesstRNA modification
Biological ProcesstRNA wobble adenosine to inosine editing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-specific adenosine deaminase subunit TAD2
  • EC number
  • Alternative names
    • tRNA-specific adenosine-34 deaminase subunit TAD2

Gene names

    • Name
      TAD2
    • ORF names
      J1246
    • Ordered locus names
      YJL035C

Organism names

Accessions

  • Primary accession
    P47058
  • Secondary accessions
    • D6VWE8

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001717401-250tRNA-specific adenosine deaminase subunit TAD2

Proteomic databases

Interaction

Subunit

Heterodimer with TAD3.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P47058TAD3 Q9URQ33EBI-18939, EBI-2094330
View interactors in UniProtKB
View CPX-1742 in Complex Portal

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-119CMP/dCMP-type deaminase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    250
  • Mass (Da)
    28,252
  • Last updated
    1996-02-01 v1
  • Checksum
    C774A1E50AA68106
MQHIKHMRTAVRLARYALDHDETPVACIFVHTPTGQVMAYGMNDTNKSLTGVAHAEFMGIDQIKAMLGSRGVVDVFKDITLYVTVEPCIMCASALKQLDIGKVVFGCGNERFGGNGTVLSVNHDTCTLVPKNNSAAGYESIPGILRKEAIMLLRYFYVRQNERAPKPRSKSDRVLDKNTFPPMEWSKYLNEEAFIETFGDDYRTCFANKVDLSSNSVDWDLIDSHQDNIIQELEEQCKMFKFNVHKKSKV

Sequence caution

The sequence CAA88261.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ242667
EMBL· GenBank· DDBJ
CAB60629.1
EMBL· GenBank· DDBJ
Genomic DNA
Z49310
EMBL· GenBank· DDBJ
CAA89326.1
EMBL· GenBank· DDBJ
Genomic DNA
AY693172
EMBL· GenBank· DDBJ
AAT93191.1
EMBL· GenBank· DDBJ
Genomic DNA
Z48229
EMBL· GenBank· DDBJ
CAA88261.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
BK006943
EMBL· GenBank· DDBJ
DAA08764.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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