P46999 · PIR5_YEAST

Function

function

Component of the outer cell wall layer (By similarity).
May be involved in meiosis and sporulation

Features

Showing features for site.

128720406080100120140160180200220240260280
TypeIDPosition(s)Description
Site62-63Cleavage; by KEX2
Site72Covalent attachment to cell wall glycan
Site91Covalent attachment to cell wall glycan
Site114Covalent attachment to cell wall glycan
Site154Covalent attachment to cell wall glycan

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Cellular Componentfungal-type cell wall
Cellular Componentfungal-type vacuole
Molecular Functionstructural constituent of cell wall
Biological Processfungal-type cell wall organization

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cell wall protein PIR5
  • Alternative names
    • Protein with internal repeats 5

Gene names

    • Name
      PIR5
    • ORF names
      J0555
    • Ordered locus names
      YJL160C

Organism names

Accessions

  • Primary accession
    P46999
  • Secondary accessions
    • D6VW27
    • Q86ZS0

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, propeptide, chain.

TypeIDPosition(s)Description
Signal1-21
PropeptidePRO_000037762322-62
ChainPRO_000001433363-287Cell wall protein PIR5

Post-translational modification

Covalently linked to beta-1,3-glucan of the inner cell wall layer via an alkali-sensitive ester linkage between the gamma-carboxyl group of glutamic acids, arising from specific glutamines within the PIR1/2/3 repeats, and hydroxyl groups of glucoses of beta-1,3-glucan chains.

Keywords

Proteomic databases

Expression

Induction

Cell cycle-regulated. Expression peaks during mitosis.

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat62-80PIR1/2/3 1
Repeat81-99PIR1/2/3 2
Repeat104-122PIR1/2/3 3
Repeat144-162PIR1/2/3 4

Domain

The PIR1/2/3 repeats are required for the covalent linkage to the cell wall (By similarity).
Their number varies among different strains of S.cerevisiae

Sequence similarities

Belongs to the PIR protein family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    287
  • Mass (Da)
    30,215
  • Last updated
    2006-05-16 v2
  • Checksum
    3E02845EA0DD7F33
MHYKKAFLASLLSSIALTAYAPPEPWATLTPSSKMDGGTTEYRTSFGLAVIPFTVTESKVKRNVISQINDGQVQVTTQKLPHPVSQIGDGQIQVTTQKVPPVVSHIVSQIGDGQLQITTAKNVVTKSTIAVPSKTVTATATSTATAVSQIHDGQVQVTISSASSSSVLSKSKLEPTKKPNNEKVIKVQACKSSGTLAITLQGGVLIDSSGRIGSIVANRQFQFDGPPPQAGAIYAGGWSITKHGTLAIGDNDVFYQCLSGTFYNLYDQSIGGQCNPVHLQTVGLVDC

Sequence caution

The sequence CAA89455.1 differs from that shown. Reason: Frameshift

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z49435
EMBL· GenBank· DDBJ
CAA89455.1
EMBL· GenBank· DDBJ
Genomic DNA Frameshift
AY260893
EMBL· GenBank· DDBJ
AAP21761.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006943
EMBL· GenBank· DDBJ
DAA08643.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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