P45972 · ZTF17_CAEEL

  • Protein
    Zinc finger transcription factor family protein 17
  • Gene
    ztf-17
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Probable transcription factor (PubMed:24885717).
Positively modulates expression of homeobox protein lin-39, perhaps by binding to regulatory regions of the lin-39 gene, acting in the vulval lineage (PubMed:24885717).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromatin
Cellular ComponentPcG protein complex
Cellular Componenttranscription regulator complex
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Functionmetal ion binding
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular FunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding
Biological Processregulation of transcription by RNA polymerase II

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Zinc finger transcription factor family protein 17

Gene names

    • Name
      ztf-17
    • ORF names
      T09A5.12

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    P45972

Proteomes

Organism-specific databases

Phenotypes & Variants

Disruption phenotype

RNAi-mediated knockdown reduces expression of homeobox protein lin-39 in vulval precursor cells at the larval L3 stage.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000654571-705Zinc finger transcription factor family protein 17

Proteomic databases

Expression

Gene expression databases

    • WBGene00011639Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P45972eps-8 G5ED333EBI-319208, EBI-2315916

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, zinc finger.

TypeIDPosition(s)Description
Region215-239Disordered
Zinc finger268-292C2H2-type 1
Zinc finger319-342C2H2-type 2

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    705
  • Mass (Da)
    78,529
  • Last updated
    2011-07-27 v3
  • Checksum
    7684C556F2388B7D
MLRYQASVYGDSYGNDYHLPVQGPSTIASSNGLRSQQSKIIKRPPTNYKSIPACRLAPRRRLFVADGNGVQKSMTSSSGVTFPPPDYMKKMKENYESGKIIYIRRNNPGMKGNQMTGRLTTINSSIRAPSYHATSMSAGSVTLDTSGSAPKYVYRLPKAEYGNKFDENRPASNMYVPAQEPPKQHFTTVPACMSMGGEVVFEEELDDEIADLGADELTGDGFNADKSPKSESPDPYLKSSGPLVQPCMTSKSPSYNLLQRNRLQTSRFACPQQDCFWRGTNEMSMKKHMLVHGPKQPVIYDKTGEAMKVQLVQPKPKGVKCSECDTFAYSRPLLLRHMYDSHGIEAPLVKRTFANREMLQSWLDSLRETHAVEFVVSSGSKKWGRGLQVHYLTCSRSGDQKERPNKKYVRPPRPSIKCGRNCMAYLKIKQNPTVSELQIEGCLHHSGHEIDHTRMVLESNELASIGAIVDAVNEGVDVLGNVETIRSYLGSSGRFRLVTENGLIEQMPIWFEQYHRDMAAFNGTGYRNNSGPIPITNPYLSMTMKPSINGNRRLPYSGMTIKKELESITMKKAVPIRFNGGQLQNLEMNSSIEEYDESKVKIEMDDEDALATQSILKDDFEEFKTEDLFGLGGGDDEILCGGEEASGVTSNIDGILAANLPDNFNDPLCGMDLATDFSGPFDDDVFDELLGLTNFNDRHNNLNIS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z36753
EMBL· GenBank· DDBJ
CAA85341.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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