P43638 · MHP1_YEAST

Function

function

Essential for the formation and/or stabilization of microtubules. Binds to microtubules in vitro.

Miscellaneous

Present with 279 molecules/cell in log phase SD medium.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentmicrotubule
Cellular Componentspindle
Molecular Functionstructural constituent of cytoskeleton
Biological Processfungal-type cell wall organization
Biological Processnegative regulation of microtubule depolymerization

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    MAP-homologous protein 1

Gene names

    • Name
      MHP1
    • ORF names
      J1206
    • Ordered locus names
      YJL042W

Organism names

Accessions

  • Primary accession
    P43638
  • Secondary accessions
    • D6VWE2

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue, chain, cross-link.

Type
IDPosition(s)Description
Modified residue1N-acetylmethionine
ChainPRO_00000727541-1398MAP-homologous protein 1
Modified residue81Phosphoserine
Cross-link221Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Modified residue222Phosphothreonine
Modified residue309Phosphoserine
Modified residue311Phosphoserine
Modified residue354Phosphoserine
Modified residue357Phosphoserine
Modified residue577Phosphothreonine

Keywords

Proteomic databases

PTM databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY P43638GLC7 P325986EBI-10880, EBI-13715

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region21-77Disordered
Compositional bias26-48Polar residues
Compositional bias60-77Polar residues
Compositional bias90-106Polar residues
Region90-144Disordered
Region156-186Disordered
Region191-210Disordered
Region244-270Disordered
Region296-382Disordered
Compositional bias320-336Basic and acidic residues
Compositional bias357-382Polar residues
Region395-428Disordered
Region515-548Disordered
Compositional bias517-548Basic and acidic residues
Compositional bias605-622Polar residues
Region605-630Disordered
Region1148-1169Disordered
Region1203-1223Disordered
Region1227-1258Tau/MAP repeat-like
Region1313-1372Disordered
Compositional bias1322-1357Polar residues

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,398
  • Mass (Da)
    155,207
  • Last updated
    1995-11-01 v1
  • Checksum
    E7925D75D80E0E58
MDSKDTQKLLKEHRIPCIDVGWLVRPSASTSKSSRPGKSESKANSVAPDIQMDTARPPVFETSVDSSSSILSSNDKGRRHSVAASLLMDNQRANAGSTSVPTNIPPPRGRSKSVVETNLSNVEADSGHHHHHRHHHHTEDAPAPKKVGFFKSLFGHRKKDQEQQEKERERKERSPSPTHVDRGAAIRRERTATISAESPPPLQYNAPPSYNDTVVPLTRSKTESEVYYENHPQSYYHGRMRTYHSPEEGKVDGTSPADDHNYGGSRPDPRLMDFLRYYKSKDYKLAAFKEGNFIKSSASPTTKKNRRASFSLHNDKPQPAKSLAHQKFDAKGRPIPPHPDAPKLPSAFRKKHPSNASIVDTVDSNSDVSSSAQNNNQTPSSHKFGAFLRKVTSYGNNNNNSTNASSLSANVNNPDTSSTSLWSSSSMEFDPSKITTVPGLENIRPLKHVSFATNTYFNDPPQQICSKNPRKGEVEVKPNGSVVIHRLTPQERKKIMESTSLGVVVGGTGQLKLLNPEEDDANAKSKEEMAPQKQNEVEAHDEEDNNSQRRNIVMAAAEAAAEARAKEAPNELKRIVTNNEEEVTVSKTASHLTIDKPMISRRGASTSSLASMVSSDTNGTNADDEGEILPPPSLKIPHDIVYTRCCHLREILPIPATLKQLKKGSTDPIPILQLRNPRPSMVEIWSFSDFLSIAPVLCLSLDGVQLTVQMLRIILSSLVYKQHFQKLSLRNTPLDEEGWKVLCYFVSKAKSLHSIDLTMVPSIKTNVQKPSKSSLKSKILRMQCNLENRSDMNWDLLTASIALMGGLEEIVISGAKMNSAQFKNFILVACIATERLGLAYNGLSKSQCDDLAKWMVQSKVTGLDVGFNDLNGKLSSFTDAVLGKIQKANEKNVFKFLSLNGTNLRVNEHDTFENNEVLKLISVLCYLENLKFLDISNNPAIFPHCVPTLIDFLPVFVNLVRLHIDYNNLSSTSVVMLAEILPMCSRLNYFSMLGTELDLASSKALAEAVRKSSSLMTLDVDYVYMPENIKEKISLYALRNIQGELKRVNSDDKDIKDSQFSSLQDQLSLLLTEKADNSEHYNKMVENFMAKIALARIKISKVVHDLFDLKLNGQLNLEGKEALIRLCFIEASLERGCDLLKQRHNNTLKSPEAVSKSRKGGNQAQPNSESCQRMLLSSSILQNSDHIALMPFGSAIVEKSSPDAEDAVEFREGDDSNVNHEDVPANDQQFRDEVDIKNKYSIIKRELEHEKLVGGGDLPVDKEILNRAAQSLDSDQIKEFLLKNDVSTILGVIDELHSQGYHLHHIFKKQGNQEETAFRTKDEQQSSQSNDSSANASPTTDPISTGSNTSRTNDNAHIPPTDAPGFDKFMNNAEENAIDAAYDDVLDKIQDARNSSTK

Features

Showing features for compositional bias, sequence conflict.

Type
IDPosition(s)Description
Compositional bias26-48Polar residues
Compositional bias60-77Polar residues
Compositional bias90-106Polar residues
Sequence conflict108in Ref. 1; CAA59145
Sequence conflict112-184in Ref. 1; CAA59145
Compositional bias320-336Basic and acidic residues
Sequence conflict331in Ref. 1; CAA59145
Compositional bias357-382Polar residues
Sequence conflict419in Ref. 1; CAA59145
Compositional bias517-548Basic and acidic residues
Sequence conflict594-595in Ref. 1; CAA59145
Compositional bias605-622Polar residues
Sequence conflict619in Ref. 1; CAA59145
Sequence conflict659-660in Ref. 1; CAA59145
Sequence conflict1175-1176in Ref. 1; CAA59145
Sequence conflict1309-1320in Ref. 1; CAA59145
Compositional bias1322-1357Polar residues
Sequence conflict1339in Ref. 1; CAA59145
Sequence conflict1356in Ref. 1; CAA59145

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X84652
EMBL· GenBank· DDBJ
CAA59145.1
EMBL· GenBank· DDBJ
Genomic DNA
Z49317
EMBL· GenBank· DDBJ
CAA89333.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006943
EMBL· GenBank· DDBJ
DAA08758.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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