P43619 · NADC_YEAST

Function

function

Involved in the catabolism of quinolinic acid (QA).

Miscellaneous

Present with 2660 molecules/cell in log phase SD medium.

Catalytic activity

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.

Features

Showing features for binding site.

129520406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site107substrate
Binding site142-144substrate
Binding site166substrate
Binding site176substrate
Binding site206substrate
Binding site227substrate
Binding site256-258substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionnicotinate-nucleotide diphosphorylase (carboxylating) activity
Biological Process'de novo' NAD biosynthetic process from tryptophan
Biological ProcessNAD biosynthetic process
Biological Processquinolinate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nicotinate-nucleotide pyrophosphorylase [carboxylating]
  • EC number
  • Alternative names
    • Quinolinate phosphoribosyltransferase [decarboxylating] (QAPRTase)

Gene names

    • Name
      BNA6
    • Synonyms
      QPT1
    • Ordered locus names
      YFR047C

Organism names

Accessions

  • Primary accession
    P43619
  • Secondary accessions
    • D6VTT0

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001559561-295Nicotinate-nucleotide pyrophosphorylase [carboxylating]

Proteomic databases

PTM databases

Interaction

Subunit

Hexamer formed by 3 homodimers.

Protein-protein interaction databases

Miscellaneous

Family & Domains

Sequence similarities

Belongs to the NadC/ModD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    295
  • Mass (Da)
    32,365
  • Last updated
    1995-11-01 v1
  • Checksum
    0680BB5DDC095050
MPVYEHLLPVNGAWRQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSGGLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKLAH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D50617
EMBL· GenBank· DDBJ
BAA09286.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006940
EMBL· GenBank· DDBJ
DAA12490.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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