STC-1 is a downstream effector molecule in latanoprost signaling that is independent of the F2a receptor equivalent and non-additive in the early intraocular pressure response in wild-type mice
Data including data from studies using transgenic mice suggest that signaling via prostaglandin-F2alpha/Ptgfr and Camk2g/p38/Foxo1 MAP kinase/calcium pathways are involved in regulation of hepatic gluconeogenesis in both obesity and fasting. (Ptgfr = prostaglandin F2alpha receptor; Camk2g = calcium-calmodulin-dependent protein kinase type 2 gamma; p38 = p38 MAP kinase; Foxo1 = forkhead box transcription factor O1)
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