P42774 · GBF1_ARATH
- ProteinG-box-binding factor 1
- GeneGBF1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids315 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter (PubMed:1373374).
G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control. Binds to the G-box motif 5'-CACGTG-3' of LHCB2.4 (At3g27690) promoter. May act as transcriptional activator in light-regulated expression of LHCB2.4. Probably binds DNA as monomer. DNA-binding activity is redox-dependent (PubMed:22718771).
G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control. Binds to the G-box motif 5'-CACGTG-3' of LHCB2.4 (At3g27690) promoter. May act as transcriptional activator in light-regulated expression of LHCB2.4. Probably binds DNA as monomer. DNA-binding activity is redox-dependent (PubMed:22718771).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | sequence-specific DNA binding | |
Molecular Function | transcription cis-regulatory region binding |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameG-box-binding factor 1
- Short namesAtGBF1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionP42774
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Features
Showing features for mutagenesis.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Mutagenesis | 247 | Significantly increases DNA binding activity. | |||
Mutagenesis | 275 | Slightly increases DNA binding activity. | |||
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 22 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000076565 | 1-315 | G-box-binding factor 1 | ||
Disulfide bond | 247 | Interchain | |||
Post-translational modification
Phosphorylated by CK2.
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Found in both light and dark grown leaves.
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-39 | Polar residues | |||
Region | 1-56 | Disordered | |||
Region | 93-268 | Disordered | |||
Compositional bias | 108-128 | Basic and acidic residues | |||
Compositional bias | 135-189 | Polar residues | |||
Domain | 222-285 | bZIP | |||
Region | 224-243 | Basic motif | |||
Compositional bias | 250-266 | Polar residues | |||
Region | 250-285 | Leucine-zipper | |||
Sequence similarities
Belongs to the bZIP family.
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
P42774-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length315
- Mass (Da)33,932
- Last updated1998-12-15 v2
- Checksum8585EF0249C91C21
P42774-2
- Name2
- Differences from canonical
- 161-162: Missing
Features
Showing features for compositional bias, sequence conflict, alternative sequence.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-39 | Polar residues | |||
Sequence conflict | 43 | in Ref. 1; CAA45356 | |||
Compositional bias | 108-128 | Basic and acidic residues | |||
Sequence conflict | 120 | in Ref. 6; AAK96765/AAL47377 | |||
Compositional bias | 135-189 | Polar residues | |||
Alternative sequence | VSP_009191 | 161-162 | in isoform 2 | ||
Sequence conflict | 249 | in Ref. 6; AAK96765/AAL47377 | |||
Compositional bias | 250-266 | Polar residues | |||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X63894 EMBL· GenBank· DDBJ | CAA45356.1 EMBL· GenBank· DDBJ | mRNA | ||
X99941 EMBL· GenBank· DDBJ | CAA68197.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z99708 EMBL· GenBank· DDBJ | CAB16806.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL161589 EMBL· GenBank· DDBJ | CAB80339.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE86694.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE86695.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY054574 EMBL· GenBank· DDBJ | AAK96765.1 EMBL· GenBank· DDBJ | mRNA | ||
AY064670 EMBL· GenBank· DDBJ | AAL47377.1 EMBL· GenBank· DDBJ | mRNA | ||
AF428382 EMBL· GenBank· DDBJ | AAL16150.1 EMBL· GenBank· DDBJ | mRNA |