P42044 · HEMH_CUCSA
- ProteinFerrochelatase-2, chloroplastic
- GeneHEMH
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids514 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the ferrous insertion into protoporphyrin IX.
Catalytic activity
- 2 H+ + heme b = Fe2+ + protoporphyrin IX
Pathway
Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Molecular Function | ferrochelatase activity | |
Biological Process | heme biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFerrochelatase-2, chloroplastic
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Cucurbitales > Cucurbitaceae > Benincaseae > Cucumis
Accessions
- Primary accessionP42044
Subcellular Location
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000008882 | ?-514 | Ferrochelatase-2, chloroplastic | |||
Sequence: MDAASSSLALSNIKLHGSTNTLNSDQRISSLCSLPKSRVTFSCKTSGNLQVRDRSTGLVVSCSSSNGDRDVIQGLHLSGPIEKKSRLGQACCSVGTFTVGEFALESQSQAVDDKVGVLLLNLGGPETLDDVQPFLYNLFADPDIIRLPRLFRFLQEPLAKLISTYRAPKSKEGYASIGGGSPLRKITDEQAQALKMALAEKNMSTNVYVGMRYWYPFTEEAIQQIKRDGITRLVVLPLYPQYSISTTGSSIRVLQKMFREDAYLSSLPVSIIKSWYQREGYIKSMADLMQAELKNFANPQEVMIFFSAHGVPVSYVENAGDPYKDQMEECICLIMQELKARGIGNEHTLAYQSRVGPVQWLKPYTDEVLVELGQKGIKSLLAVPVSFVSEHIETLEEIDMEYKHLALESGIQNWGRVPALNCNSSFISDLADAVIEALPSATALAPHTSSTDADDHDPFLYAIKLLFGSVLAFILLLSPKAFMVFRNNFLLNYTRIYGYRGERSEFFWVRLIFT | ||||||
Transit peptide | 1-? | Chloroplast |
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length514
- Mass (Da)57,207
- Last updated1995-11-01 v1
- ChecksumAF85085363B44582
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
D26106 EMBL· GenBank· DDBJ | BAA05102.1 EMBL· GenBank· DDBJ | mRNA |