P41956 · C560_CAEEL
- ProteinSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Genemev-1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids182 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity).
Mediates resistance to enteropathogenic E.coli infection (PubMed:16091039).
Mediates resistance to enteropathogenic E.coli infection (PubMed:16091039).
Cofactor
Note: The heme is bound between the two transmembrane subunits.
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) | |
Cellular Component | mitochondrion | |
Cellular Component | respiratory chain complex II | |
Molecular Function | electron transfer activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | defense response to Gram-negative bacterium | |
Biological Process | determination of adult lifespan | |
Biological Process | innate immune response | |
Biological Process | mitochondrial electron transport, succinate to ubiquinone | |
Biological Process | negative regulation of response to oxidative stress | |
Biological Process | positive regulation of response to oxidative stress | |
Biological Process | response to oxidative stress | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionP41956
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane, topological domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 65-94 | Helical | ||||
Sequence: LTWMLSGFHRISGCVMAGTLLVGGIGFAVL | ||||||
Topological domain | 95-114 | Mitochondrial intermembrane | ||||
Sequence: PFDFTAFVDFIRSWNLPCAV | ||||||
Transmembrane | 115-139 | Helical | ||||
Sequence: TAVFKYIIAFPIIFHTLNGIRFLGF | ||||||
Topological domain | 140-147 | Mitochondrial matrix | ||||
Sequence: DLAKGVNN | ||||||
Transmembrane | 148-169 | Helical | ||||
Sequence: VGQIYKSGYLVSGLSAILALAI | ||||||
Topological domain | 170-172 | Mitochondrial intermembrane | ||||
Sequence: VFN |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000003637 | ?-182 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | |||
Sequence: MINIPTAILCRLGARSSISRSFGTSIVTKSEAKTPIQKFGWEYLLKQRSKNRPIAPHLTVYQPQLTWMLSGFHRISGCVMAGTLLVGGIGFAVLPFDFTAFVDFIRSWNLPCAVTAVFKYIIAFPIIFHTLNGIRFLGFDLAKGVNNVGQIYKSGYLVSGLSAILALAIVFNSCQNKSNKTA | ||||||
Transit peptide | 1-? | Mitochondrion |
Proteomic databases
Expression
Developmental stage
Is expressed at a constant level throughout development.
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length182
- Mass (Da)19,982
- Last updated1995-11-01 v1
- Checksum5E3E6DA6B08E4C5F
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0K3AU58 | A0A0K3AU58_CAEEL | mev-1 | 115 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
L26545 EMBL· GenBank· DDBJ | AAA20081.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z29443 EMBL· GenBank· DDBJ | CAA82572.1 EMBL· GenBank· DDBJ | Genomic DNA |