P41772 · AMT1_CANGA
- ProteinMetal-activated transcriptional activator protein AMT1
- GeneAMT1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids265 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Trans-acting regulatory protein that activates transcription of the MT genes (metallothionein) in response to copper or silver ions.
Features
Showing features for dna binding, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
DNA binding | 1-40 | Copper-fist | |||
Binding site | 11 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 14 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 23 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 25 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | copper ion binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
Molecular Function | transcription cis-regulatory region binding | |
Molecular Function | zinc ion binding | |
Biological Process | intracellular copper ion homeostasis | |
Biological Process | intracellular iron ion homeostasis | |
Biological Process | positive regulation of transcription by RNA polymerase II | |
Biological Process | transcription initiation at RNA polymerase II promoter |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameMetal-activated transcriptional activator protein AMT1
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Nakaseomyces
Accessions
- Primary accessionP41772
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000194927 | 1-265 | Metal-activated transcriptional activator protein AMT1 | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length265
- Mass (Da)29,426
- Last updated1995-11-01 v1
- MD5 Checksum164D0657E13A14678BE7568FAA8003E3
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 113-129 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M69146 EMBL· GenBank· DDBJ | AAA35271.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CR380955 EMBL· GenBank· DDBJ | CAG60367.1 EMBL· GenBank· DDBJ | Genomic DNA |