Isolation and characterization of XE169, a novel human gene that escapes X-inactivation.Wu J., Ellison J., Salido E., Yen P., Mohandas T., Shapiro L.J.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)TissueFibroblastCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mol. Genet. 3:153-160 (1994)Cited in1
A novel X gene with a widely transcribed Y-linked homologue escapes X- inactivation in mouse and human.Agulnik A.I., Mitchell M.J., Mattei M.-G., Borsani G., Avner P.A., Lerner J.L., Bishop C.E.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA] OF 280-344TissueBloodCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mol. Genet. 3:879-884 (1994)Cited in2Mapped to13
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.Christensen J., Agger K., Cloos P.A.C., Pasini D., Rose S., Sennels L., Rappsilber J., Hansen K.H., Salcini A.E., Helin K.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 128:1063-1076 (2007)Cited in5Mapped to4
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.Iwase S., Lan F., Bayliss P., de la Torre-Ubieta L., Huarte M., Qi H.H., Whetstine J.R., Bonni A., Roberts T.M., Shi Y.View abstractCited forFUNCTION, MUTAGENESIS OF HIS-514, CHARACTERIZATION OF VARIANTS MRXSCJ PRO-388; LEU-642; PHE-731 AND CYS-751CategoriesFunction, Sequences, Disease & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 128:1077-1088 (2007)Cited in41Mapped to16
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.Tahiliani M., Mei P., Fang R., Leonor T., Rutenberg M., Shimizu F., Li J., Rao A., Shi Y.View abstractCited forFUNCTION, SUBUNIT, MUTAGENESIS OF HIS-514, SUBCELLULAR LOCATION, CHARACTERIZATION OF VARIANTS MRXSCJ GLY-87; TYR-402 AND CYS-751CategoriesFunction, Sequences, Disease & Variants, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 447:601-605 (2007)Cited in1Mapped to21
Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.Horton J.R., Engstrom A., Zoeller E.L., Liu X., Shanks J.R., Zhang X., Johns M.A., Vertino P.M., Fu H., Cheng X.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIESCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 291:2631-2646 (2016)Cited in3Mapped to3
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.Tumber A., Nuzzi A., Hookway E.S., Hatch S.B., Velupillai S., Johansson C., Kawamura A., Savitsky P., Yapp C.[...], Brennan P.E.View abstractCited forFUNCTION, ACTIVITY REGULATION, MUTAGENESIS OF 514-HIS--GLU-516CategoriesFunction, Disease & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Chem. Biol. 24:371-380 (2017)Cited in7
Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization.Mukherjee S., Adhikary S., Gadad S.S., Mondal P., Sen S., Choudhari R., Singh V., Adhikari S., Mandal P.[...], Das C.View abstractCited forINTERACTION WITH ZMYND8CategoryInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Death Dis. 11:1073-1073 (2020)Cited in3Mapped to6
Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein.Koehler C., Bishop S., Dowler E.F., Schmieder P., Diehl A., Oschkinat H., Ball L.J.View abstractCited forSTRUCTURE BY NMR OF 73-188CategoryStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiomol. NMR. Assign. 2:9-11 (2008)Cited in1
Structural analysis of human KDM5B guides histone demethylase inhibitor development.Johansson C., Velupillai S., Tumber A., Szykowska A., Hookway E.S., Nowak R.P., Strain-Damerell C., Gileadi C., Philpott M.[...], Oppermann U.View abstractCited forX-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 384-772 IN COMPLEX WITH MANGANESE AND ZINCCategoriesInteraction, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Chem. Biol. 12:539-545 (2016)Cited in3Mapped to1
Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation.Jensen L.R., Amende M., Gurok U., Moser B., Gimmel V., Tzschach A., Janecke A.R., Tariverdian G., Chelly J.[...], Lenzner S.View abstractCited forVARIANTS MRXSCJ PRO-388; TYR-402; LYS-698 AND PHE-731, TISSUE SPECIFICITYCategoriesSequences, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAm. J. Hum. Genet. 76:227-236 (2005)Cited in1
A novel mutation in JARID1C gene associated with mental retardation.Santos C., Rodriguez-Revenga L., Madrigal I., Badenas C., Pineda M., Mila M.View abstractCited forVARIANT MRXSCJ ARG-451CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEur. J. Hum. Genet. 14:583-586 (2006)Cited in1Mapped to3
Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.Tzschach A., Lenzner S., Moser B., Reinhardt R., Chelly J., Fryns J.-P., Kleefstra T., Raynaud M., Turner G.[...], Jensen L.R.View abstractCited forVARIANTS MRXSCJ GLY-87; LEU-642; TRP-750 AND CYS-751CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mutat. 27:389-389 (2006)Cited in1Mapped to3
A de novo paradigm for mental retardation.Vissers L.E., de Ligt J., Gilissen C., Janssen I., Steehouwer M., de Vries P., van Lier B., Arts P., Wieskamp N.[...], Veltman J.A.View abstractCited forVARIANT TYR-640CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 42:1109-1112 (2010)Cited in8
Multilocus loss of DNA methylation in individuals with mutations in the histone H3 lysine 4 demethylase KDM5C.Grafodatskaya D., Chung B.H., Butcher D.T., Turinsky A.L., Goodman S.J., Choufani S., Chen Y.A., Lou Y., Zhao C.[...], Weksberg R.View abstractCited forVARIANT MRXSCJ LEU-480CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBMC Med. Genomics 6:1-1 (2013)Cited in1Mapped to3
Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity.Brookes E., Laurent B., Ounap K., Carroll R., Moeschler J.B., Field M., Schwartz C.E., Gecz J., Shi Y.View abstractCited forCHARACTERIZATION OF VARIANTS MRXSCJ TYR-402 AND LEU-480CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mol. Genet. 24:2861-2872 (2015)Cited in1Mapped to3