P41121 · PNP_PHOLU
- ProteinPolyribonucleotide nucleotidyltransferase
- Genepnp
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids709 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
Catalytic activity
- phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)
Cofactor
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | magnesium ion binding | |
Molecular Function | polyribonucleotide nucleotidyltransferase activity | |
Molecular Function | RNA binding | |
Biological Process | mRNA catabolic process | |
Biological Process | RNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyribonucleotide nucleotidyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Photorhabdus
Accessions
- Primary accessionP41121
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000197915 | 1-709 | Polyribonucleotide nucleotidyltransferase | |||
Sequence: MLNPIVRKFQYGQHTVTIETGMMARQATAAVMVNMDDTAVFVTVVGQKKVKAGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPGEGETLVARLIDRPLRPLFPEGFLNEVRIVATVVSVNPQINPDIVAMIGASAALALSGIPFNGPIGAARVGYINDQYVLNPTSDELKNSRLDLVVSGTAGAVLMVESEADLLTEEQMLGAVVFGHDQQQVVIDNINALAAEAGKEKWDWVPEPVNQALHDRVAELAESRLGDAYRITEKQERYAQVDAIKDEVTAALLEQDETLEEAEIHEILGSLEKNVVRSRVLSGEPRIDGREKDMVRALDVRTGVLPRTHGSALFTRGETQALVTATLGTERDAQIIDELMGERTDRFLLHYNFPPYSVGETGMMGSPKRREIGHGRLAKRGVLAVMPKANEFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGSCEGISALQMDIKIEGITREIMQVALNQAKGARLHILSVMEQAITTPRDDISQFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAISRIEEITAEIEVGRIYAGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVADYLQVGQETSVKVLEIDRQGRVRLSIKEATAGTAVEEAPPAPQSAE |
Expression
Induction
In response to low temperature.
Interaction
Subunit
Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 553-612 | KH | ||||
Sequence: PRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAISRI | ||||||
Domain | 622-690 | S1 motif | ||||
Sequence: GRIYAGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVADYLQVGQETSVKVLEIDRQGRVRLSIK |
Sequence similarities
Belongs to the polyribonucleotide nucleotidyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length709
- Mass (Da)76,745
- Last updated1995-02-01 v1
- ChecksumEBFCC559FC921E6B
Keywords
- Technical term