P40441 · HXT12_YEAST
- ProteinPutative hexose transporter 12
- GeneHXT12
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids457 (go to sequence)
- Protein existenceUncertain
- Annotation score2/5
Function
function
Probable glucose transporter.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | glucose transmembrane transporter activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended namePutative hexose transporter 12
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionP40441
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-2 | Cytoplasmic | ||||
Sequence: MG | ||||||
Transmembrane | 3-23 | Helical; Name=1 | ||||
Sequence: LIVSIFNIGCAIGGIVLSKVG | ||||||
Topological domain | 24-29 | Extracellular | ||||
Sequence: DIYGRR | ||||||
Transmembrane | 30-50 | Helical; Name=2 | ||||
Sequence: IGLITVTAIYVVGILIQITSI | ||||||
Topological domain | 51-60 | Cytoplasmic | ||||
Sequence: NKWYQYFIGR | ||||||
Transmembrane | 61-81 | Helical; Name=3 | ||||
Sequence: IISGIGVGGIAVLSPMLISEV | ||||||
Topological domain | 82-87 | Extracellular | ||||
Sequence: APKHIR | ||||||
Transmembrane | 88-108 | Helical; Name=4 | ||||
Sequence: GTLVQLYQLMGTMGIFLGYCT | ||||||
Topological domain | 109-122 | Cytoplasmic | ||||
Sequence: NYGTKNYHNATQWR | ||||||
Transmembrane | 123-143 | Helical; Name=5 | ||||
Sequence: VGLGLCFAWATFMVSGMMFVP | ||||||
Topological domain | 144-247 | Extracellular | ||||
Sequence: ESPRYLIEVGKDEEAKHSLSKSNKVSVDDPALLAEYDTIKAGIEIEKLAGNASWSELLSTKTKVFQRVLMGVIIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQ | ||||||
Transmembrane | 248-268 | Helical; Name=6 | ||||
Sequence: TSIIIGVVNFFSSFIAVYTIE | ||||||
Topological domain | 269-274 | Cytoplasmic | ||||
Sequence: RFGRRT | ||||||
Transmembrane | 275-295 | Helical; Name=7 | ||||
Sequence: CLLWGAASMLCCFAVFASVGV | ||||||
Topological domain | 296-319 | Extracellular | ||||
Sequence: TKLWPQGSSHQDITSQGAGNCMIV | ||||||
Transmembrane | 320-340 | Helical; Name=8 | ||||
Sequence: FTMFFIFSFATTWAGGCFVIV | ||||||
Topological domain | 341-353 | Cytoplasmic | ||||
Sequence: SETFPLRAKSRGM | ||||||
Transmembrane | 354-374 | Helical; Name=9 | ||||
Sequence: AIATAANWMWGFLISFFTPFI | ||||||
Topological domain | 375-379 | Extracellular | ||||
Sequence: TGAIN | ||||||
Transmembrane | 380-400 | Helical; Name=10 | ||||
Sequence: FYYGYVFLGCLVFAYFYVFFF | ||||||
Topological domain | 401-457 | Cytoplasmic | ||||
Sequence: VPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000050408 | 1-457 | Putative hexose transporter 12 | |||
Sequence: MGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGIGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKHSLSKSNKVSVDDPALLAEYDTIKAGIEIEKLAGNASWSELLSTKTKVFQRVLMGVIIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCFVIVSETFPLRAKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS | ||||||
Glycosylation | 194 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
PTM databases
Structure
Sequence
- Sequence statusComplete
- Length457
- Mass (Da)50,830
- Last updated1995-02-01 v1
- ChecksumFBEE8186BAC88B88