P40354 · NTA1_YEAST

Function

function

Deamidates N-terminal Asn and Gln. Component of a targeting complex in the N-end rule pathway.

Miscellaneous

Present with 1640 molecules/cell in log phase SD medium.

Caution

It is uncertain whether Met-1 or Met-11 is the initiator.

Features

Showing features for active site.

145750100150200250300350400450
TypeIDPosition(s)Description
Active site63Proton acceptor
Active site136Proton donor
Active site187Nucleophile

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionprotein-N-terminal asparagine amidohydrolase activity
Molecular Functionprotein-N-terminal glutamine amidohydrolase activity
Biological Processprotein catabolic process
Biological Processprotein modification process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein N-terminal amidase
  • EC number
  • Short names
    NT-amidase

Gene names

    • Name
      NTA1
    • ORF names
      J1742
    • Ordered locus names
      YJR062C

Organism names

Accessions

  • Primary accession
    P40354
  • Secondary accessions
    • D6VWN3

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002040681-457Protein N-terminal amidase

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-453CN hydrolase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    457
  • Mass (Da)
    51,897
  • Last updated
    1995-02-01 v1
  • Checksum
    E6259FBBFB25A889
MLIDAIHGAKMSTKLLVSLKVLVIQLNPQIGQVDQTIKRTWSILDKVTKSATYVKPDIILFPEFALTGYSFHARKDILPYVTKKDEGPSFELAKSISEKFQCYTIIGYPEDDDEQKLYNSALVVNPQGEQIFNYRKTFLYDTEMNWDCEENPEGFQTFPMDFSKCAKLSNEDSYNRDVTLKASIGICMDLSPYKFMAPFNHFEFSSFCVDNNVELILCPMAWLNSTSITDKQTLHNNSLLEAAKNKIAFALKEQGLPLAGSQGIYQLKIGDSQRTPRVPSDDSTSEYKDMDEPDMSNVNYWILRFFPFLYFKSRINWFKNSSLIESILGKTRMPLDHEYYKDGKHKEDTIDLLDSEEVIKDTVLEKTFLGTSLGQPWKFQGKNAILVLANRCGTEDGTTIFAGSSGIYKFNGKKPKGSQDDDESSLDSLNESVELLGNLGKGLEGAILREVQFEVFR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
L35564
EMBL· GenBank· DDBJ
AAB59320.1
EMBL· GenBank· DDBJ
Genomic DNA
Z49562
EMBL· GenBank· DDBJ
CAA89590.1
EMBL· GenBank· DDBJ
Genomic DNA
L47993
EMBL· GenBank· DDBJ
AAB39288.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006943
EMBL· GenBank· DDBJ
DAA08849.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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