P39967 · UBP9_YEAST

Function

Miscellaneous

Present with 98 molecules/cell in log phase SD medium.

Catalytic activity

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
    EC:3.4.19.12 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

1754100200300400500600700
TypeIDPosition(s)Description
Active site143Nucleophile
Active site618Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentnucleus
Molecular Functioncysteine-type deubiquitinase activity
Biological Processprotein deubiquitination
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Ubiquitin carboxyl-terminal hydrolase 9
  • EC number
  • Alternative names
    • Deubiquitinating enzyme 9
    • Ubiquitin thioesterase 9
    • Ubiquitin-specific-processing protease 9

Gene names

    • Name
      UBP9
    • Ordered locus names
      YER098W

Organism names

Accessions

  • Primary accession
    P39967
  • Secondary accessions
    • D3DM05

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000805941-754Ubiquitin carboxyl-terminal hydrolase 9

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-76Disordered
Compositional bias9-34Basic and acidic residues
Compositional bias35-76Polar residues
Domain134-667USP
Compositional bias194-210Polar residues
Region194-273Disordered
Compositional bias236-270Basic and acidic residues
Region726-754Disordered
Compositional bias738-754Basic residues

Sequence similarities

Belongs to the peptidase C19 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    754
  • Mass (Da)
    86,244
  • Last updated
    1995-02-01 v1
  • Checksum
    D2C03D233D14D693
MIKRWLSVNRKKSHPEKNTQGNDEINRKATSLKKTKGSGDPSIAKSPSAKSSTSSIPSNLASHERRSKFSSQTDNLAGNKHYHEHYHNMASTSDEREYDSSTTYEDRAFDTESSILFTTITDLMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNIPEFRCNVLRYPERVAAVNRIRKSDLKGSKIRVFTNESFETSTNSGNSNTGYQSNDNEDAHNHHHLQQSDQDNSSSSTQEKQNNFERKRNSFMGFGKDKSNYKDSAKKDDNNEMERPQPVHTVVMASDTLTEKLHEGCKKIIVGRPLLKQSDSLSKASTTDCQANSHCQCDSQGSRITSVDDDVLVNPESCNDAVNNSNNNKENTFPTSEQRKKAALIRGPVLNVDHLLYPTEEATLYNGLKDIFESITENLSLTGIVSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQKTDNSNDNFITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVYKKYELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFYKETQADKTENQNENIDTSSQDQMQTDNNIEQLIKCDDWLRDRKLRAAANIERKKTLGNIPEVKTAETKTPLNDKKRNKQKRKSRILSFIK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias9-34Basic and acidic residues
Compositional bias35-76Polar residues
Compositional bias194-210Polar residues
Compositional bias236-270Basic and acidic residues
Compositional bias738-754Basic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U18839
EMBL· GenBank· DDBJ
AAB64653.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006939
EMBL· GenBank· DDBJ
DAA07759.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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