P39715 · ECM1_YEAST

Function

function

Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus.

Miscellaneous

Present with 2840 molecules/cell in log phase SD medium.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleolus
Cellular Componentnucleus
Cellular Componentpreribosome, large subunit precursor
Biological Processribosomal large subunit export from nucleus

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Shuttling pre-60S factor ECM1
  • Alternative names
    • Extracellular mutant protein 1
    • Protein SIM1

Gene names

    • Name
      ECM1
    • Synonyms
      SIM1
    • Ordered locus names
      YAL059W

Organism names

Accessions

  • Primary accession
    P39715
  • Secondary accessions
    • D6VPG0
    • E9P8V4

Proteomes

Organism-specific databases

Subcellular Location

Note: Shuttles between the nucleus and the cytoplasm and is re-imported by the KAP123 karyopherin.

Keywords

PTM/Processing

Features

Showing features for chain, modified residue (large scale data), modified residue.

Type
IDPosition(s)Source
Description
ChainPRO_00000869161-212UniProtShuttling pre-60S factor ECM1
Modified residue (large scale data)39PTMeXchangePhosphoserine
Modified residue (large scale data)104PTMeXchangePhosphoserine
Modified residue (large scale data)107PTMeXchangePhosphoserine
Modified residue (large scale data)147PTMeXchangePhosphoserine
Modified residue (large scale data)171PTMeXchangePhosphoserine
Modified residue188UniProtPhosphoserine
Modified residue (large scale data)188PTMeXchangePhosphoserine
Modified residue (large scale data)194PTMeXchangePhosphothreonine
Modified residue (large scale data)198PTMeXchangePhosphothreonine
Modified residue (large scale data)200PTMeXchangePhosphothreonine

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Associates with the pre-60S ribosomal particle and the nucleopore complex.

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region28-48Disordered
Region188-212Disordered
Compositional bias191-201Polar residues

Sequence similarities

Belongs to the ECM1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    212
  • Mass (Da)
    23,891
  • Last updated
    2011-07-27 v2
  • MD5 Checksum
    07D24923ED6A305A4318B7AE93C660BF
MWEQRRQKVVFSLTILVRYRLKQSMAKKISKNSRAARQSDALEPEVKDLSELPRAEKTDLTNILIRTAAKNEALLEAKISKKANKSKRGKKLNKKALEDKLANSISSMDRDRLVKALNFTNRLDGKIAKSISRAKYIQNTRKAGWDSTNETIKKELAFLNGGLSVQAKSASEGNAEKEDEEIPEVFDSLAEDNTVQKTPTNRFGVLPDDVEE

Features

Showing features for sequence conflict, compositional bias.

Type
IDPosition(s)Description
Sequence conflict102in Ref. 1; AAC04975
Compositional bias191-201Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U12980
EMBL· GenBank· DDBJ
AAC04975.1
EMBL· GenBank· DDBJ
Genomic DNA
AY558168
EMBL· GenBank· DDBJ
AAS56494.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006935
EMBL· GenBank· DDBJ
DAA06930.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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