P38971 · ALP1_YEAST
- ProteinBasic amino-acid permease
- GeneALP1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids573 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
High-affinity permease for basic amino acids.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | membrane | |
Molecular Function | amino acid transmembrane transporter activity | |
Molecular Function | basic amino acid transmembrane transporter activity | |
Biological Process | amino acid transmembrane transport | |
Biological Process | basic amino acid transport |
Keywords
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameBasic amino-acid permease
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionP38971
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Topological domain | 1-73 | Cytoplasmic | |||
Transmembrane | 74-93 | Helical | |||
Topological domain | 94-95 | Extracellular | |||
Transmembrane | 96-116 | Helical | |||
Topological domain | 117-153 | Cytoplasmic | |||
Transmembrane | 154-174 | Helical | |||
Topological domain | 175-179 | Extracellular | |||
Transmembrane | 180-200 | Helical | |||
Topological domain | 201-209 | Cytoplasmic | |||
Transmembrane | 210-230 | Helical | |||
Topological domain | 231-265 | Extracellular | |||
Transmembrane | 266-286 | Helical | |||
Topological domain | 287-306 | Cytoplasmic | |||
Transmembrane | 307-327 | Helical | |||
Topological domain | 328-359 | Extracellular | |||
Transmembrane | 360-380 | Helical | |||
Topological domain | 381-403 | Cytoplasmic | |||
Transmembrane | 404-424 | Helical | |||
Topological domain | 425-431 | Extracellular | |||
Transmembrane | 432-452 | Helical | |||
Topological domain | 453-477 | Cytoplasmic | |||
Transmembrane | 478-498 | Helical | |||
Topological domain | 499-510 | Extracellular | |||
Transmembrane | 511-531 | Helical | |||
Topological domain | 532-573 | Cytoplasmic | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000054145 | 1-573 | Basic amino-acid permease | ||
Proteomic databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 40-66 | Disordered | |||
Compositional bias | 42-66 | Basic and acidic residues | |||
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length573
- Mass (Da)64,014
- Last updated1996-10-01 v2
- MD5 Checksum2DE24E3C8A5678506A16804E840102C3
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 42-66 | Basic and acidic residues | |||
Sequence conflict | 51 | in Ref. 1; CAA52199 | |||
Sequence conflict | 126 | in Ref. 1; CAA52199 | |||
Sequence conflict | 260 | in Ref. 1; CAA52199 | |||
Sequence conflict | 517 | in Ref. 1; CAA52199 | |||
Sequence conflict | 548 | in Ref. 1; CAA52199 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X74069 EMBL· GenBank· DDBJ | CAA52199.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
X92494 EMBL· GenBank· DDBJ | CAA63228.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z71546 EMBL· GenBank· DDBJ | CAA96177.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006947 EMBL· GenBank· DDBJ | DAA10290.1 EMBL· GenBank· DDBJ | Genomic DNA |